The validity of the OSA-18 among three groups of pediatric patients
| Autor: | Nina L. Shapiro, Alexandra Carrer, Ali M. Strocker |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
medicine.medical_specialty
Pediatrics Adolescent Cross-sectional study Palatine Tonsil Population Physical examination California Surveys and Questionnaires medicine Humans Mass Screening Child Intensive care medicine Prospective cohort study education Physical Examination Mass screening Sleep Apnea Obstructive education.field_of_study Leukemia medicine.diagnostic_test business.industry Case-control study Sleep apnea Hypertrophy General Medicine medicine.disease Kidney Transplantation Lymphoproliferative Disorders Liver Transplantation Obstructive sleep apnea Cross-Sectional Studies Otorhinolaryngology Case-Control Studies Child Preschool Adenoids Pediatrics Perinatology and Child Health business |
| Zdroj: | International Journal of Pediatric Otorhinolaryngology. 69:241-247 |
| ISSN: | 0165-5876 |
| DOI: | 10.1016/j.ijporl.2004.09.005 |
| Popis: | Summary Objective: To compare the signs and symptoms of obstructive sleep apnea syndrome in three groups of pediatric patients; solid organ transplant recipients, healthy children, and children with leukemia; in order to examine the effects of chronic illness on the obstructive sleep apnea—18-item questionnaire and to investigate its validity as a screening tool for obstructive sleep apnea in the pediatric solid organ transplant population. Methods: In this cross-sectional study, there were two hundred and six subjects; 46 kidney transplant recipients, 59 liver transplant recipients, 34 patients with leukemia, and 67 healthy children. Adenotonsillar enlargement was assessed by using the obstructive sleep apnea—18-item questionnaire and by performing a focused physical examination of the oral and nasal cavity at the time of the child's routine visit in either the transplant clinic, outpatient oncology center, or general pediatric clinic. Results: Comparison of questionnaire scores amongst the three groups showed significant differences between the healthy children and liver transplant recipients as well as those with leukemia. There was a significant difference in the physical examination scores of the children with leukemia as compared to the other groups. Conclusions: Adenotonsillar enlargement in pediatric transplant recipients can be an early indication of post-transplantation lymphoproliferative disorder. However, the prevalence of adenotonsillar enlargement in the transplant population does not appear to differ from that of the healthy population. Additionally, scores on the OSA-18 in the transplant population were confounded by chronic illness. Further prospective studies need to be performed to develop a screening tool to identify transplant recipients at risk for post-transplantation adenotonsillar lymphoma. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect