High-Nutrition Biscuits to Increase Animal Protein in Diets of HIV-Infected Kenyan Women and Their Children: A Study in Progress

Autor: Grace Ettyang, Judith A. Ernst, Charlotte G. Neumann
Rok vydání: 2014
Předmět:
Rural Population
and promotion of well-being
Activities of daily living
Health Status
Geography
Planning and Development

Psychological intervention
HIV Infections
law.invention
Randomized controlled trial
law
Medicine
Food science
Child
Triticum
Pediatric
education.field_of_study
Nutrition and Dietetics
food and beverages
Vitamin B 12
Zinc
Infectious Diseases
HIV-positive women
Child
Preschool

HIV/AIDS
Zero Hunger
Female
Dietary Proteins
Nutritive Value
Kenya
Meat
Iron
Clinical Trials and Supportive Activities
Food supplement
Population
Nutritional Status
Article
Acquired immunodeficiency syndrome (AIDS)
Clinical Research
Environmental health
Animals
Humans
Vitamin B12
Preschool
3.3 Nutrition and chemoprevention
education
Nutrition
vitamin B-12
Nutrition & Dietetics
business.industry
Prevention
Lysine
Infant
Prevention of disease and conditions
medicine.disease
Diet
Dietary Supplements
Lean body mass
Soybeans
protein
business
Food Science
Zdroj: Food and nutrition bulletin, vol 35, iss 4 Suppl
ISSN: 1564-8265
0379-5721
DOI: 10.1177/15648265140354s306
Popis: BackgroundPreliminary evidence suggests that improved nutrition early in HIV infection may delay progression to AIDS and delay the initiation or improve the effectiveness of antiretroviral drug therapy. There are few studies that evaluate food-based interventions in drug-naïve, HIV-infected women and their children. Meat provides several nutrients identified as important in maintaining immune function and lean body mass.ObjectiveTo design supplemental meat and soybean biscuits for use in a randomized trial examining the effect of meat in the diet of drug-naïve, HIV-infected rural Kenyan women on changes in weight, lean body mass, morbidity, nutritional status, and activities of daily living of the women and growth and development of their children.MethodsWe designed three supplemental biscuits: one with added dried beef another with added soybean flour, and a wheat biscuit to serve as a control biscuit to be used in a randomized feeding intervention in drug-naïve, HIV-infected rural Kenyan women and their children. The nutritional contents of the different types of biscuit were examined and compared.ResultsThe three biscuits were isocaloric. Meat biscuits provided more lysine, vitamin B12, and bioavailable zinc. Soybean biscuits provided more total and absorbable iron; however, higher fiber and phytate contents may inhibit nutrient absorption. Data analysis for clinical outcomes of the trial is ongoing.ConclusionsThe "biscuit model" is useful for nutrition supplementation studies because it can be provided in a blinded and randomized fashion, safely and privately in a home under directly observed consumption by a highly stigmatized population. It is well received by adults and children, and the biscuits can be produced locally with available, simple, affordable technology.
Databáze: OpenAIRE