Bilateral familial phaeochromocytomata with paroxysmal hypertension; successful surgical removal of tumors in two cases, with discussion of certain diagnostic procedures and physiological considerations

Autor: Evan Calkins, John Eager Howard
Rok vydání: 2010
Předmět:
Zdroj: The Journal of clinical endocrinology and metabolism. 7(7)
ISSN: 0021-972X
Popis: SUCCESSFUL surgical removal of a phaeochromocytoma is still a relatively rare accomplishment. A review of the available world's literature at this date has yielded reports of 176 such tumors, but only 47 of these were proven to be endocrinologically active by cessation of symptoms following surgical removal. The inherent difficulties in dealing with patients suffering from phaeochromocytomata are many. They may be divided into three categories and briefly listed as follows: 1. A. Diagnosis: Although the classical syndrome produced by such tumors is striking and clear cut (18), any individual case may lack one or more of the features which would ordinarily direct attention toward the correct diagnosis. Especially difficult are those patients in whom a permanent sustained hypertension is manifested and in whom the clinical diagnosis of essential hypertension may be made.1 2. B. Localization: When reasonable certainty of the presence of a phaeochromocytoma exists, localization of the offending tumor is often...
Databáze: OpenAIRE