Spiropyrimidinetrione DNA Gyrase Inhibitors with Potent and Selective Antituberculosis Activity

Autor:	Preshendren Govender, Rudolf Müller, Kawaljit Singh, Virsinha Reddy, Charles J. Eyermann, Stephen Fienberg, Sandeep R. Ghorpade, Lizbé Koekemoer, Alissa Myrick, Dirk Schnappinger, Curtis Engelhart, Jaclynn Meshanni, Jo Ann W. Byl, Neil Osheroff, Vinayak Singh, Kelly Chibale, Gregory S. Basarab
Rok vydání:	2022
Předmět:	DNA Gyrase Gram-Negative Bacteria Drug Discovery Antitubercular Agents Topoisomerase II Inhibitors Molecular Medicine Microbial Sensitivity Tests Mycobacterium tuberculosis Gram-Positive Bacteria Article Anti-Bacterial Agents
Zdroj:	J Med Chem
ISSN:	1520-4804 0022-2623
DOI:	10.1021/acs.jmedchem.2c00266
Popis:	This is the accepted manuscript version of the work published in its final form as Govender, P., Müller, R., Singh, K., Reddy, V., Eyermann, C. J., Fienberg, S., Ghorpade, S. R., Koekemoer, L., Myrick, A., Schnappinger, D., Engelhart, C., Meshanni, J., Byl, J. A. W., Osheroff, N., Singh, V., Chibale, K., & Basarab, G. S. (2022). Spiropyrimidinetrione DNA Gyrase Inhibitors with Potent and Selective Antituberculosis Activity.Journal of Medicinal Chemistry,65(9), 6903-6925. https://doi.org/10.1021/acs.jmedchem.2c00266 Deposited byshareyourpaper.organdopenaccessbutton.org. We've taken reasonable steps to ensure this content doesn't violate copyright. However, if you think it does you can request a takedown by emailinghelp@openaccessbutton.org.
Databáze:	OpenAIRE
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