The relationship of fetuin-A and lactoferrin with bone mass in elderly women
| Autor: | Anuk Kruavit, La-or Chailurkit, R. Rajatanavin, Boonsong Ongphiphadhanakul |
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| Rok vydání: | 2010 |
| Předmět: |
musculoskeletal diseases
medicine.medical_specialty alpha-2-HS-Glycoprotein Endocrinology Diabetes and Metabolism Bone resorption Collagen Type I Absorptiometry Photon N-terminal telopeptide Bone Density Internal medicine medicine Humans Bone Resorption Femoral neck Aged Bone mineral Aged 80 and over Lumbar Vertebrae biology business.industry Lactoferrin Femur Neck Fetuin Peptide Fragments Procollagen peptidase medicine.anatomical_structure Endocrinology Parathyroid Hormone biology.protein Female business Peptides Type I collagen Procollagen |
| Zdroj: | Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 22(7) |
| ISSN: | 1433-2965 |
| Popis: | The relationships of fetuin-A and lactoferrin to bone-related phenotypes were investigated in elderly women. Fetuin-A was associated not only with bone mineral density (BMD) but also with bone resorption marker suggesting an influence of fetuin-A on osteoclasts. The aim of this study is to investigate the relationship of bone-related phenotypes in elderly women with circulating fetuin-A and lactoferrin. Eighty-two elderly women were studied. Serum fetuin-A, lactoferrin, C-terminal telopeptide of type I collagen (CTx), total procollagen type 1 amino-terminal propeptide, and plasma intact parathyroid hormone (PTH) were analyzed. BMD of the lumbar spine at L2–4 and at the femoral neck was measured. Serum fetuin-A was significantly associated with L2–4 BMD (r = 0.23, P |
| Databáze: | OpenAIRE |
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