Ultrasound as a Valuable Imaging Modality in Sclerosing Lymphocytic Lobulitis: Imaging Features Based on a Retrospective Cohort Analysis of 51 Cases
| Autor: | Ulysses dos Santos Torres, Monica Maria Agata Stiepcich, André F. Reis, Lucy Tiemi Sato, Giselle Guedes Netto de Mello, Henrique Manoel Lederman, Tatiana Cardoso de Mello Tucunduva |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
medicine.medical_specialty Lymphocytosis 030218 nuclear medicine & medical imaging Cohort Studies 03 medical and health sciences Breast Diseases 0302 clinical medicine Diabetes mellitus Benign breast condition Medicine Mammography Humans Radiology Nuclear Medicine and imaging Breast Aged Retrospective Studies Modality (human–computer interaction) Sclerosis medicine.diagnostic_test business.industry Ultrasound Retrospective cohort study General Medicine Limiting Sclerosing lymphocytic lobulitis Middle Aged medicine.disease 030220 oncology & carcinogenesis Female Radiology Ultrasonography Mammary business |
| Zdroj: | Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes. 72(4) |
| ISSN: | 1488-2361 |
| Popis: | Purpose: Sclerosing lymphocytic lobulitis (SLL) is a rare benign breast condition usually associated with diabetes mellitus and whose imaging features have been assessed in few studies, limiting the adoption of diagnostic guidelines. We aimed to identify the main morphological features associated with SLL on imaging examinations (mainly ultrasound and mammography) and to retrospectively evaluate the role that each method played in the diagnostic workup (detection and indication for biopsy). Methods: A retrospective study was conducted in a high-volume single center, encompassing 51 consecutive patients (100% female; 26-78 y; 43.7 ± 15.5 y) with histopathologically proven SLL (59 lesions; 0.5-6.1 cm). Results: Most lesions (31/59; 53%) were found in asymptomatic individuals. Ultrasound detected 91.1% (51 out of 56 lesions assessed by this modality), of which 94.1% were non-circumscribed masses (BI-RADS® 4). Mammography detected 41.6% (15 out of 36 lesions assessed by this modality), with a predominance (80%) of non-calcified ones (masses, asymmetries and distortion). Two-year follow-up was achieved in 29 lesions (49%), showing complete remission (45%) or stability (41%) in most cases. Conclusions: Most lesions in this retrospective sample have been detected by means of ultrasound and had their need for biopsy indicated by this modality. Female diabetic patients younger than 40 years presenting with a palpable lesion and a non-circumscribed mass on ultrasound could be submitted to core biopsy; histopathologic findings suggestive of SLL should be considered concordant in this scenario, with subsequent conservative treatment. |
| Databáze: | OpenAIRE |
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