The effects of Plasma-Lyte 148 solution on blood coagulation: an in-vitro, volunteer study using rotational thromboelastometry
| Autor: | Hyun Jeong Shin, Hyo Seok Na, Jung Pyo Hong, Sanghwan Do, Gwan Woo Lee, Hee Yeon Park |
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| Rok vydání: | 2018 |
| Předmět: |
Male
Volunteers Serial dilution Sodium Acetate Magnesium Chloride rotational thromboelastometry Sodium Chloride Gluconates Potassium Chloride blood coagulation 03 medical and health sciences 0302 clinical medicine 030202 anesthesiology Coagulation profile Medicine Humans Volunteer fluid business.industry 030208 emergency & critical care medicine Plasma-Lyte 148 Hematology General Medicine Venous blood Original Articles Clot formation Dilution Thrombelastography Thromboelastometry Coagulation Anesthesia hemodilution Female Blood Coagulation Tests business |
| Zdroj: | Blood Coagulation & Fibrinolysis |
| ISSN: | 1473-5733 |
| Popis: | The current study aimed to measure the effects of Plasma-Lyte 148 solution on the blood coagulation profile according to the hemodilution level using rotational thromboelastometry (ROTEM) tests. Venous blood was collected from 12 healthy volunteers and divided into four specimen bottles, which were diluted at different levels with Plasma-Lyte 148 (0, 20, 40, and 60%). Following this, ROTEM tests were performed on the study samples. We found that as the hemodilution level increased, the ROTEM values showed a hypocoagulable pattern. The change rate of the maximum clot firmness (MCF) of INTEM was greater in the 40 (P = 0.015) and 60% (P |
| Databáze: | OpenAIRE |
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