Hepatitis B and C
| Autor: | Daniel H. Leung, Krupa R. Mysore |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Viral Hepatitis Vaccines Cirrhosis Adolescent Hepatitis C virus medicine.disease_cause 03 medical and health sciences 0302 clinical medicine Hepatitis B Chronic medicine Humans Child Hepatitis B virus Hepatitis Hepatology business.industry Infant Newborn virus diseases Infant Hepatitis B Hepatitis C Chronic medicine.disease Virology digestive system diseases 030104 developmental biology Hepatocellular carcinoma Child Preschool 030211 gastroenterology & hepatology business Viral hepatitis Oncovirus |
| Zdroj: | Clinics in liver disease. 22(4) |
| ISSN: | 1557-8224 |
| Popis: | Hepatitis B virus (HBV) and hepatitis C virus (HCV) infections represent a major global public health and economic burden, with an estimated 257 million and 71 million people, respectively, having chronic infection worldwide. The natural history of HBV and HCV in children depends on age at time of infection, mode of acquisition, ethnicity, and genotype. Most children infected perinatally or vertically remain asymptomatic but are at uniquely higher risk of developing chronic viral hepatitis, progressing to liver cirrhosis and hepatocellular carcinoma (HCC), hence classifying HBV and HCV as oncoviruses. This article discusses the epidemiology, virology, immunobiology, prevention, clinical manifestations, evaluation, and the advances in treatment of hepatitis B and C in children. |
| Databáze: | OpenAIRE |
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