Relationship between Retinal Vascular Occlusions and Cognitive Dementia in a Large Cross-Sectional Cohort
| Autor: | Katherine J. Bangen, Alison X. Chan, Mathieu F. Bakhoum, Christine Y. Bakhoum |
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| Rok vydání: | 2021 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Retinal Artery Occlusion Population Article Risk Factors Retinal Vein Occlusion Odds Ratio Prevalence Humans Medicine Dementia education Stroke Aged Retrospective Studies Aged 80 and over Retinal Vascular Occlusion education.field_of_study business.industry Medical record medicine.disease Ophthalmology Cross-Sectional Studies Cohort Population study Female Diagnosis code business |
| Zdroj: | Am J Ophthalmol |
| ISSN: | 0002-9394 |
| DOI: | 10.1016/j.ajo.2021.01.026 |
| Popis: | • PURPOSE: To examine the association between cognitive dementia and retinal vascular occlusions. • DESIGN: A retrospective, cross-sectional study. • METHODS: Single-institution study population: we reviewed the electronic medical records of 37,208 individuals older than 65 years of age who were evaluated by an ophthalmologist or an optometrist and who also had a medical visit to our institution over a 6-year period. Individuals with and without retinal vascular occlusions were identified by International Classification of Diseases, version 10 (ICD-10) diagnostic codes. • MAIN OUTCOME: we analyzed the association between dementia and retinal vascular occlusions after adjusting for covariates which included age, sex, stroke, diabetes mellitus, and hypertension using multiple logistic regression analyses. • RESULTS: Compared to subjects without retinal vascular occlusions, those with retinal vascular occlusions had a higher prevalence of dementia (6.7% vs. 9.3%, respectively; P < .001). After adjusting for either age or stroke, there were no significant associations between retinal vascular occlusions and dementia. • CONCLUSIONS: Individuals with retinal vascular occlusions have a higher prevalence of dementia. However, this association is secondary to shared underlying risk factors in this population, such as older age and stroke. |
| Databáze: | OpenAIRE |
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