The Yield of Community-Based 'Retrospective' Tuberculosis Contact Investigation in a High Burden Setting in Ethiopia

Autor: Dereje Habte, Belaineh Girma, Endale Shibeshi, Mitiku Ensermu, G Nigussie, Yared Kebede Haile, Pedro Suarez, Shallo Daba Hamusse, Zewdu Gashu, Nebiyu Hiruy, Degu Jerene, Yewulsew Kassie, Muluken Melese
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Bacterial Diseases
Male
Health Screening
Endemic Diseases
Physiology
Cancer Treatment
Tuberculosis Contact
lcsh:Medicine
Pathology and Laboratory Medicine
Logistic regression
Geographical Locations
0302 clinical medicine
Medicine and Health Sciences
Coughing
Odds Ratio
Public and Occupational Health
030212 general & internal medicine
Child
lcsh:Science
Community based
Multidisciplinary
Middle Aged
Body Fluids
Infectious Diseases
Oncology
Child
Preschool
Tuberculosis Diagnosis and Management
Female
Anatomy
medicine.symptom
Research Article
Adult
medicine.medical_specialty
Tuberculosis
Adolescent
Yield (finance)
Research and Analysis Methods
03 medical and health sciences
Signs and Symptoms
Diagnostic Medicine
Active tb
medicine
Humans
Tuberculosis
Pulmonary
Retrospective Studies
business.industry
lcsh:R
Sputum
Biology and Life Sciences
Infant
Mycobacterium tuberculosis
Odds ratio
Tropical Diseases
medicine.disease
Surgery
Mucus
Cross-Sectional Studies
Logistic Models
030228 respiratory system
Specimen Preparation and Treatment
People and Places
Africa
lcsh:Q
Ethiopia
Contact Tracing
Physiological Processes
business
Demography
Zdroj: PLoS ONE, Vol 11, Iss 8, p e0160514 (2016)
PLoS ONE
ISSN: 1932-6203
Popis: Objective To determine the yield and determinants of retrospective TB contact investigation in selected zones in Ethiopia. Materials and Methods This was a community-based cross-sectional study conducted during June-October 2014.Trained lay providers performed symptom screening for close contacts of index cases with all types of TB registered for anti-TB treatment within the last three years. We used logistic regression to determine factors associated with TB diagnosis among the contacts. Results Of 272,441 close contacts of 47, 021 index cases screened, 13,886 and 2, 091 had presumptive and active TB respectively. The yield of active TB was thus 768/100, 000, contributing 25.4% of the 7,954 TB cases reported from the study zones over the study period. The yield was highest among workplace contacts (12,650/100, 000). Active TB was twice more likely among contacts whose index cases had been registered for TB treatment within the last 12 months compared with those who had been registered 24 or more months earlier (adjusted odds ratio, AOR: 1.77 95% CI 1.42–2.21). Sex or clinical type of TB in index cases was not associated with the yield. Smear negative (SS-) index cases (AOR: 1.74 955 CI 1.13–2.68), having index cases who registered for treatment within
Databáze: OpenAIRE
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