Extent of hypoattenuation on CT angiography source images in basilar artery occlusion : Prognostic value in the Basilar Artery International Cooperation Study

Autor: Puetz, Volker, Khomenko, Andrei, Hill, Michael D., Dzialowski, Imanuel, Michel, Patrik, Weimar, Christian, Wijman, Christine A. C., Mattle, Heinrich P., Engelter, Stefan T., Muir, Keith W., Pfefferkorn, Thomas, Tanne, David, Szabo, Kristina, Jaap Kappelle, L., Algra, Ale, Von Kummer, Ruediger, Demchuk, Andrew M., Schonewille, Wouter J., Kappelle, L. Jaap
Jazyk: angličtina
Rok vydání: 2011
Předmět:
ISSN: 0039-2499
Popis: Background and Purpose— The posterior circulation Acute Stroke Prognosis Early CT Score (pc-ASPECTS) quantifies the extent of early ischemic changes in the posterior circulation with a 10-point grading system. We hypothesized that pc-ASPECTS applied to CT angiography source images predicts functional outcome of patients in the Basilar Artery International Cooperation Study (BASICS). Methods— BASICS was a prospective, observational registry of consecutive patients with acute symptomatic basilar artery occlusion. Functional outcome was assessed at 1 month. We applied pc-ASPECTS to CT angiography source images of patients with CT angiography for confirmation of basilar artery occlusion. We calculated unadjusted and adjusted risk ratios (RRs) of pc-ASPECTS dichotomized at ≥8 versus Results— Of 158 patients included, 78 patients had a CT angiography source images pc-ASPECTS ≥8. Patients with a pc-ASPECTS ≥8 more often had a favorable outcome than patients with a pc-ASPECTS Conclusions— pc-ASPECTS on CT angiography source images independently predicted death and functional independence at 1 month in the CT angiography subgroup of patients in the BASICS registry.
Databáze: OpenAIRE