Long-term followup of a bladder carcinoma cohort: questionable value of radical radiotherapy
| Autor: | Sonny L. Johansson, Hans Hedelin, Goran Borghede, Sten Holmang |
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| Rok vydání: | 1997 |
| Předmět: |
Male
medicine.medical_specialty Time Factors medicine.medical_treatment Urology Carcinoma Medicine Humans External beam radiotherapy Prospective Studies Aged Neoplasm Staging Aged 80 and over Urinary bladder business.industry Radical radiotherapy Middle Aged medicine.disease Surgery Radiation therapy Survival Rate medicine.anatomical_structure Long term followup Urinary Bladder Neoplasms Cohort Female business Complication Follow-Up Studies |
| Zdroj: | The Journal of urology. 157(5) |
| ISSN: | 0022-5347 |
| Popis: | Purpose: We studied the outcome of radical radiotherapy for bladder carcinoma in all patients from a well-defined region.Materials and Methods: All 701 cases with a new bladder carcinoma between 1987 and 1988 in Western Sweden were prospectively documented and followed until 1994. Between 1987 and 1994, 74 of the 701 patients (mean age 73 years, range 54 to 88) were treated with external beam radiotherapy (60 Gy. or more).Results: At least 84% of the patients had persistent tumor, a local recurrence or a symptomatic contracted bladder after external beam radiotherapy. Seven patients (9.5%) died of early or late treatment related complications. Of only 8 long-term survivors 6 had undergone radical transurethral resection before external beam radiotherapy.Conclusions: Full dose external beam radiotherapy in patients with bladder carcinoma was associated with high local recurrence and serious complication rates. It must be questioned whether elderly patients actually benefit from full dose radiotherapy. |
| Databáze: | OpenAIRE |
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