Supplement of bamboo extract lowers serum monocyte chemoattractant protein-1 concentration in mice fed a diet containing a high level of saturated fat
| Autor: | Wanyu Liu, Jun Panee, Jason K. Higa, Marla J. Berry |
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| Rok vydání: | 2011 |
| Předmět: |
Male
Chemokine medicine.medical_specialty Intra-Abdominal Fat Saturated fat Medicine (miscellaneous) Type 2 diabetes Diet High-Fat Poaceae Article Mice Dry weight Internal medicine medicine Animals Endocrine system Chemokine CCL2 Nutrition and Dietetics biology Plant Extracts Monocyte Organ Size biology.organism_classification medicine.disease Mice Inbred C57BL medicine.anatomical_structure Endocrinology Phyllostachys edulis Dietary Supplements Immunology biology.protein |
| Zdroj: | British Journal of Nutrition. 106:1810-1813 |
| ISSN: | 1475-2662 0007-1145 |
| Popis: | Monocyte chemoattractant protein-1 (MCP-1) is an inflammatory chemokine up-regulated in obese subjects, contributing to the development of type 2 diabetes. The present study investigated the inhibitory effect of an ethanol–water extract from bamboo (BEX,Phyllostachys edulis) on the blood concentration of MCP-1. C57BL/6J mice were fed a standard diet or a high-fat diet with or without the BEX supplement (11 g dry mass/17 000 kJ) for 6 months. A total of ten mice were used in each group. Body weight and food consumption were measured weekly. After euthanisation, the weight of visceral fat and circulating MCP-1 concentration were measured. In comparison with the standard control group, the high-fat control group had increased body weight, abdominal fat storage and serum MCP-1 concentration by 60 % (P P P P P P |
| Databáze: | OpenAIRE |
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