Evaluation of treatment adherence in patients with Behçet’s disease: its relation to disease manifestations, patients’ beliefs about medications, and quality of life
| Autor: | Esraa M. Seif, Basma M Medhat, Hania S. Zayed |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Behcet's disease Disease Medication Adherence Young Adult 03 medical and health sciences 0302 clinical medicine Rheumatology Quality of life Internal medicine medicine Humans In patient 030212 general & internal medicine Glucocorticoids Socioeconomic status Aged 030203 arthritis & rheumatology business.industry Behcet Syndrome Anti-Inflammatory Agents Non-Steroidal Anticoagulants General Medicine Middle Aged medicine.disease Tubulin Modulators Cross-Sectional Studies Antirheumatic Agents Cohort Linear Models Quality of Life Female Colchicine business Vasculitis Attitude to Health Immunosuppressive Agents |
| Zdroj: | Clinical Rheumatology. 38:761-768 |
| ISSN: | 1434-9949 0770-3198 |
| Popis: | Despite its importance, adherence to treatment has not been sufficiently studied in Behçet's disease (BD). The aim of this study was to evaluate medication adherence in BD using the Compliance Questionnaire of Rheumatology (CQR) and factors potentially affecting it.This cross-sectional study included 67 consecutive BD patients including 57 (85%) males with a mean age of 35.1 ± 9.27 years and mean disease duration of 129 ± 91 months. The cumulative clinical manifestations, the Behçet's Disease Current Activity Form (BDCAF) score, and the Vasculitis Damage Index (VDI) were recorded. The CQR, Socioeconomic Status Questionnaire for Health Research in Egypt (SES), the Beliefs about Medication Questionnaire (BMQ), and the Short Form 36 (SF-36) quality of life assessment questionnaire were administered to the patients. Linear regression analysis was done to determine independent predictors of CQR.The mean BDCAF score was 3.27 ± 3.54 and the VDI was 3.36 ± 2.21. The mean CQR score was 69.2 ± 11.79. The CQR score varied significantly among different health sources (p = 0.02), with no relationship detected with other sociodemographic characteristics, nor with clinical characteristics or the SF-36. Among the investigated medications' complexities, severity of side effects showed significantly different CQR scores (p = 0.004), and a weak positive correlation between medications' numbers and the CQR was detected. Predictors for higher CQR scores included the necessity beliefs score of the BMQ (β = 1.1, p 0.001); whereas, predictors for lower CQR scores were the harm and concern BMQ subscales ((β = - 1.5, p = 0.004) and (β = - 0.72, p = 0.032), respectively).Beliefs about medications were the only predictor for adherence in our cohort. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink