Small hepatocellular carcinoma associated with Wilson's disease
| Autor: | Masanori Abe, Norio Horiike, Sk. Md. Fazle Akbar, Morikazu Onji, Toshikazu Masumoto, Hideto Iuchi, Kojiro Michitaka, Koji Joko, Teru Kumagi, Kiyotaka Kurose |
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| Rok vydání: | 2005 |
| Předmět: |
Male
medicine.medical_specialty Pathology Carcinoma Hepatocellular medicine.medical_treatment Biopsy Gastroenterology Diagnosis Differential Fatal Outcome Hepatolenticular Degeneration Diathermy Internal medicine Internal Medicine Carcinoma medicine Humans Embolization Chemoembolization Therapeutic Microwaves Ultrasonography medicine.diagnostic_test business.industry Liver Neoplasms Ceruloplasmin General Medicine Middle Aged medicine.disease digestive system diseases Wilson's disease Liver Liver biopsy Hepatocellular carcinoma Abnormal Liver Function Test Differential diagnosis business Tomography X-Ray Computed Copper |
| Zdroj: | Internal medicine (Tokyo, Japan). 44(5) |
| ISSN: | 0918-2918 |
| Popis: | We report a 66-year-old male patient with hepatocellular carcinoma (HCC) associated with Wilson's disease. The patient presented with unresolving abnormal liver function test, decreased serum ceruloplasmin levels and increased 24-hour urine copper excretion. Liver biopsy specimen revealed the presence of increased levels of copper and features suggestive of Wilson's disease. Abdominal imaging showed the existence of a small HCC. Three years after chemoembolization and microwave coagulation therapy for HCC, he died of hepatic failure, which apparently resulted from chemoembolization. Patients with Wilson's disease should be screened for HCC. We should elude therapies such as chemoembolization in these patients. |
| Databáze: | OpenAIRE |
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