Silica gel-promoted synthesis of 3,4,5-triaryltetrahydro-1,4-thiazine derivatives from β,β′-dichloro sulfides and aromatic amines

Autor:	Yoshio Ishino, Takatoshi Ito, Masatoshi Mihara, Mitsuo Komatsu, Satoshi Minakata, Yoji Oderaotoshi
Rok vydání:	2005
Předmět:	chemistry.chemical_compound chemistry Thiazine Silica gel Yield (chemistry) Organic Chemistry Drug Discovery Organic chemistry Sulfur dichloride General Medicine Biochemistry Adduct
Zdroj:	Tetrahedron Letters. 46:8105-8108
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2005.09.119
Popis:	A novel and efficient synthesis of 3,4,5-triaryltetrahydro-1,4-thiazine derivatives by treatment of β,β′-dichloro sulfides, 2:1 adducts of alkenes and sulfur dichloride, with aromatic amines in the presence of silica gel is described. The silica gel can be easily recovered and reused in up to four consecutive reactions without any significant decrease in product yield.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99448cd0088a37a96714f7a14b17d1e7 https://doi.org/10.1016/j.tetlet.2005.09.119 Zobrazit plný text záznamu Full Text from ScienceDirect