Mannitol oxidation in two Micromonospora isolates and in representative species of other actinomycetes
| Autor: | L. R. Fare, M E Shearer, Claude H. Nash, R. J. Mehta |
|---|---|
| Rok vydání: | 1977 |
| Předmět: |
Dehydrogenase
Micromonospora Applied Microbiology and Biotechnology Microbiology Actinomycetales medicine Mannitol chemistry.chemical_classification Cell-Free System Ecology biology Phosphotransferases digestive oral and skin physiology Nocardia biology.organism_classification Alcohol Oxidoreductases Enzyme Mannitol dehydrogenase Biochemistry chemistry Streptomyces lavendulae Oxidation-Reduction Research Article Food Science Biotechnology medicine.drug |
| Zdroj: | Applied and Environmental Microbiology. 33:1013-1015 |
| ISSN: | 1098-5336 0099-2240 |
| Popis: | Mannitol kinase and mannitol-1-phosphate dehydrogenase activities were detected in two Micromonospora isolates. The presence of these enzyme activities indicates that mannitol is catabolized first to mannitol-1-phosphate and then to fructose-6-phosphate. Mannitol-oxidizing enzymes were also surveyed in representative species of four other genera of actinomycetes. Mannitol-1-phosphate dehydrogenase was detected in cell-free extracts of Streptomyces lactamdurans. In contrast, cell-free extracts of Mycobacterium smegmatis, Nocardia erythrophila, Streptomyces lavendulae, and Actinoplanes missouriensis contained mannitol dehydrogenase activity but no detectable mannitol-1-phosphate dehydrogenase activity. The mannitol dehydrogenase activities in the latter species support the operation of a pathway for catabolism of mannitol that involves the oxidation of mannitol to fructose, followed by phosphorylation to fructose-6-phosphate. |
| Databáze: | OpenAIRE |
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