Urinary tract infections due to extended-spectrum beta-lactamase-producing Gram-negative bacteria: identification of risk factors and outcome predictors in an Australian tertiary referral hospital
| Autor: | Sarah L. McGuinness, Aaron Z. Wagen, Damon P. Eisen, Michael Osthoff |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Microbiology (medical)
Adult Male Pediatrics medicine.medical_specialty medicine.drug_class Antibiotic resistance Urinary system Antibiotics Bacteriuria Tertiary referral hospital urologic and male genital diseases beta-Lactamases law.invention lcsh:Infectious and parasitic diseases Tertiary Care Centers law Risk Factors Epidemiology medicine Humans lcsh:RC109-216 Aged Aged 80 and over Urinary tract infection business.industry Australia General Medicine Odds ratio Length of Stay Middle Aged medicine.disease Prognosis bacterial infections and mycoses Intensive care unit female genital diseases and pregnancy complications Anti-Bacterial Agents Community-Acquired Infections Intensive Care Units Infectious Diseases ESBL Gram-negative bacteria Urinary Tract Infections Female business |
| Zdroj: | International Journal of Infectious Diseases, Vol 34, Iss C, Pp 79-83 (2015) |
| ISSN: | 1878-3511 1201-9712 |
| Popis: | Objectives: Extended-spectrum beta-lactamase-expressing Gram-negative bacilli (ESBL-GNB) now commonly cause community-acquired infections, including urinary tract infections (UTI), and represent a challenge for practitioners in choosing empirical antibiotics. The aim of this study was to describe the epidemiology and clinical characteristics of UTIs/bacteriuria due to ESBL-GNB in Australia. Methods: At a single-site tertiary referral hospital, 100 cases with UTIs/bacteriuria due to ESBL-GNB were matched to 100 cases where UTIs/bacteriuria were caused by organisms matching the ESBL bacterial species that had routine susceptibility to antibiotics. Potential risk factors for ESBL-GNB UTI/bacteriuria and differences in clinical outcomes were identified. Results: Length of admission prior to positive sample (odds ratio (OR) 1.3, p = 0.03, per week), exposure to antibiotics (OR 5.7, p |
| Databáze: | OpenAIRE |
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