Patient Perspectives on Outcome Domains of Medication Adherence Trials in Inflammatory Arthritis: An International OMERACT Focus Group Study
Autor: | Maarten de Wit, Susan J. Bartlett, Charlotte L Bekker, Vicki Evans, Bart J F van den Bemt, Mary A. De Vera, Sacha Bossina, Ayano Kelly, Beverley Shea, Dawn P. Richards, Allison Tong, Marieke Scholte-Voshaar, Kathleen Tymms, Lyn March, Peter Tugwell |
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Rok vydání: | 2021 |
Předmět: |
Adult
Male medicine.medical_specialty Immunology Physical fitness MEDLINE Psychological intervention Medication Adherence Healthcare improvement science Radboud Institute for Health Sciences [Radboudumc 18] Arthritis Rheumatoid All institutes and research themes of the Radboud University Medical Center Rheumatology Health care medicine Humans Immunology and Allergy Aged Motivation business.industry Focus Groups Middle Aged Focus group Clinical trial Antirheumatic Agents Family medicine Female Thematic analysis business Qualitative research |
Zdroj: | The Journal of Rheumatology, 48, 1480-1487 The Journal of Rheumatology, 48, 9, pp. 1480-1487 |
ISSN: | 1499-2752 0315-162X |
Popis: | ObjectiveTo describe the perspectives of patients with inflammatory arthritis (IA) on outcome domains of trials evaluating medication adherence interventions.MethodsAdult patients (≥ 18 yrs) with IA taking disease-modifying antirheumatic drugs from centers across Australia, Canada, and the Netherlands participated in 6 focus groups to discuss outcome domains that they consider important when participating in medication adherence trials. We analyzed the transcripts using inductive thematic analysis.ResultsOf the 38 participants, 23 (61%) had rheumatoid arthritis and 21 (55%) were female. The mean age was 57.3 ± (SD 15.0) years. Improved outcome domains that patients wanted from participating in an adherence trial were categorized into 5 types: medication adherence, adherence-related factors (supporting adherence; e.g., medication knowledge), pathophysiology (e.g., physical functioning), life impact (e.g., ability to work), and economic impact (e.g., productivity loss). Three overarching themes reflecting why these outcome domains matter to patients were identified: how taking medications could improve patients’ emotional and physical fitness to maintain their social function; how improving knowledge and confidence in self-management increases patients’ trust and motivation to take medications as agreed with minimal risk of harms; and how respect and reassurance, reflecting health care that values patients’ opinions and is sensitive to patients’ individual goals, could improve medication-taking behavior.ConclusionPatients value various outcome domains related to their overall well-being, confidence in medication use, and patient–healthcare provider relationships to be evaluated in future adherence trials. |
Databáze: | OpenAIRE |
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