Effect of Passion Fruit Seed Extract Rich in Piceatannol on the Skin of Women: A Randomized, Placebo-Controlled, Double-Blind Trial
| Autor: | Minoru Morita, Hiroko Maruki-Uchida, Masahiko Sai, Yoshikazu Yonei |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Adult Antioxidant medicine.medical_treatment Medicine (miscellaneous) Human skin Placebo Antioxidants 03 medical and health sciences chemistry.chemical_compound Feces Animal science Double-Blind Method Surveys and Questionnaires Dry skin Stilbenes Medicine Humans Perspiration Skin Piceatannol Transepidermal water loss Nutrition and Dietetics business.industry Passiflora Plant Extracts food and beverages Middle Aged 030104 developmental biology chemistry Seeds Female medicine.symptom Passion fruit business |
| Zdroj: | Journal of nutritional science and vitaminology. 64(1) |
| ISSN: | 1881-7742 |
| Popis: | Piceatannol has been reported to have a wide variety of effects on the skin, including promoting collagen production, inhibiting melanin synthesis, inducing the antioxidant glutathione, and eliminating reactive oxygen species. In this study, a randomized, placebo-controlled, double-blind trial was conducted to clinically evaluate the effects of piceatannol-rich passion fruit seed extract on the skin of healthy Japanese women (age, 35-54 y). Thirty-two women with dry skin received either passion fruit seed extract (5 mg piceatannol) or a placebo (dextrin) for 8 wk. Skin hydration and other parameters on the face were assessed at 0, 4, and 8 wk by using specialized equipment. Furthermore, questionnaire interviews were conducted regarding the physical condition of subjects at 0, 4, and 8 wk. The results showed that consumption of passion fruit seed extract led to significant increases in the moisture content of human skin after 4 and 8 wk compared with that before the trial. The amount of transepidermal water loss decreased over time, although the differences were not significant. Moreover, a stratified analysis of subjects with moisture values of ≤200 μS revealed increased moisture content in the passion fruit seed extract group as compared with the placebo group. Furthermore, the results of questionnaires showed significant reductions in "perspiration" and "fatigue" in the passion fruit seed extract group as compared with the placebo group. These results indicate that oral intake of passion fruit seed extract that is rich in piceatannol could improve the moisture of dry skin and reduce fatigue. |
| Databáze: | OpenAIRE |
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