Video game therapy on mobility and dual tasking in multiple sclerosis: study protocol for a randomised controlled trial
| Autor: | Giulia Fregna, Nino Basaglia, Sofia Straudi, Giulia Zani, Giacomo Severini, Andrea Baroni, Giada Milani |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Activities of daily living Multiple Sclerosis medicine.medical_treatment statistics & research methods Timed Up and Go test law.invention NO Young Adult Quality of life (healthcare) Physical medicine and rehabilitation research methods Randomized controlled trial law medicine Humans Video game Postural Balance Randomized Controlled Trials as Topic Rehabilitation business.industry Neuropsychology rehabilitation medicine Cognition General Medicine Exercise Therapy Video Games Time and Motion Studies Quality of Life Medicine statistics & business |
| Zdroj: | BMJ Open, Vol 11, Iss 10 (2021) BMJ Open |
| ISSN: | 2044-6055 0335-3974 |
| Popis: | IntroductionMultiple sclerosis (MS) is one of the major causes of disability in young adults and affects mobility, compromising daily living activities and participation in social life. Cognitive domain is also frequently impaired in people with MS (PwMS), particularly the capacity to perform dual-task activities. Impaired cognitive processing abilities need to be treated, and motor and cognitive aspects need to be considered together. Recently, video game therapy (VGT) has been used in rehabilitation to improve motor outcomes and cognitive processing speed. The aim of this study is to test the efficacy of commercially available VGT on mobility and dual tasking in PwMS compared with standardised balance platform training (BPT).Methods and analysisThis will be a parallel-assignment, double-blinded, randomised control trial. Forty-eight (24 per arm) PwMS with Expanded Disability Status Scale 4–5.5 will be randomly assigned to receive 1 hour training session over 4 weeks (three sessions/week) of either: (1) VGT on commercial video game console to train balance and mobility-related activities or (2) BPT to perform balance, postural stability and weight-shifting exercises with and without visual feedback. The same assessor will evaluate outcome measures at points: before and after the 12 training sessions and at 3 months of follow-up. The primary outcome will be functional mobility, assessed by the Timed Up and Go test. We will also evaluate gait, risk of fall, fatigue and health-related quality of life as well as cognitive and psychological aspects (depression, anxiety and attentional performance) and stability through posturographic evaluation. Dual-tasking assessment will be performed combining posturographic and neuropsychological tests. Data analysis will be performed to compare the efficacy of the two treatments.Ethics and disseminationEthical approval have been granted from the local Ethics Committee. Study results will be communicated through high-quality journals and national and international conferences.Trial registration numberNCT03353974 |
| Databáze: | OpenAIRE |
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