Monitoring Breathing Rate at Home Allows Early Identification of COPD Exacerbations
| Autor: | Aina M. Yañez, Dolores Guerrero, Rigoberto Pérez de Alejo, Francisco Garcia-Rio, Jose Luis Alvarez-Sala, Miriam Calle-Rubio, Rosa Malo de Molina, Manuel Valle Falcones, Piedad Ussetti, Jaume Sauleda, Enrique Zamora García, Jose Miguel Rodríguez-González-Moro, Mercedes Franco Gay, Maties Torrent, Alvar Agustí |
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| Rok vydání: | 2012 |
| Předmět: |
Male
Pulmonary and Respiratory Medicine medicine.medical_specialty Time Factors Respiratory rate medicine.medical_treatment Monitoring Ambulatory Critical Care and Intensive Care Medicine Sensitivity and Specificity Severity of Illness Index Cohort Studies Pulmonary Disease Chronic Obstructive Oxygen therapy Severity of illness medicine Humans In patient Prospective Studies Prospective cohort study Aged Aged 80 and over COPD business.industry Respiration Oxygen Inhalation Therapy medicine.disease Hospitalization ROC Curve Anesthesia Respiratory Mechanics Physical therapy Respiratory frequency Female Cardiology and Cardiovascular Medicine business Follow-Up Studies Cohort study |
| Zdroj: | Chest. 142:1524-1529 |
| ISSN: | 0012-3692 |
| DOI: | 10.1378/chest.11-2728 |
| Popis: | Respiratory frequency increases during exacerbations of COPD (ECOPD). We hypothesized that this increase can be detected at home before ECOPD hospitalization.To test this hypothesis, respiratory frequency was monitored at home daily for 3 months in 89 patients with COPD (FEV₁, 42.3% ± 14.0%; reference) who were receiving domiciliary oxygen therapy (9.6 ± 4.0 h/d).During follow-up, 30 patients (33.7%) required hospitalization because of ECOPD. In 21 of them (70%), mean respiratory frequency increased (vs baseline) during the 5 days that preceded it (from 15.2 ± 4.3/min to 19.1 ± 5.9/min, P.05). This was not the case in patients without ECOPD (16.1 ± 4.8/min vs 15.9 ± 4.9/min). Receiver operating characteristic analysis showed that 24 h before hospitalization, a mean increase of 4.4/min (30% from baseline) provided the best combination of sensitivity (66%) and specificity (93%) (area under the curve [AUC] = 0.79, P.05). Two days before hospitalization, a mean increase of 2.3/min (15% change from baseline) was associated with a sensitivity of 72% and a specificity of 77% (AUC = 0.76, P.05).Respiratory frequency can be monitored daily at home in patients with COPD receiving domiciliary oxygen therapy. In these patients, breathing rate increases significantly days before they require hospitalization because of ECOPD. This may offer a window of opportunity for early intervention. |
| Databáze: | OpenAIRE |
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