Natural orifice transluminal endoscopic one-anastomosis gastric bypass: a feasibility study using porcine model

Autor: Hock Soo Ong, Zhen Jin Lee, Jeremy Tan, Baldwin Yeung, Tiffany Jian Ying Lye, Chin Hong Lim
Rok vydání: 2021
Předmět:
Zdroj: Surgical endoscopy. 35(10)
ISSN: 1432-2218
Popis: Endoscopic bariatric therapies (EBT) are emerging as effective therapies in the management of overweight patient with or without metabolic syndrome. Unfortunately most procedures only restrict the gastric volume without altering the underlying metabolism which is seen in surgical patients. The aim of this study was to investigate the feasibility and limitations of a natural orifice trans-luminal endoscopic surgery (NOTES) one anastomosis gastric bypass (OAGB). NOTES OAGB was performed in three porcine models. The steps of the procedure can be divide as follows: All the animals underwent successful NOTES of OAGB. The mean weight for the animals was 34.3 kg (32–37 kg). The mean procedure time was 250 min (300 min for first animal and 180 min for third animal). The average bypassed bilio-pancreatic limb was 98 cm (range 65–130 cm). This study has provided proof-of-principle in a preclinical model that a NOTES approach can be used to perform OAGB and, therefore, merits additional evaluation and consideration.
Databáze: OpenAIRE