The effects of oral clonidine on the growth hormone level in acromegalic patients
| Autor: | F. A. László, Zs. Valkusz, L. Gáspár, Tamás Janáky |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Adult
Male Pituitary gland medicine.medical_specialty Endocrinology Diabetes and Metabolism medicine.medical_treatment Administration Oral Growth hormone Clonidine chemistry.chemical_compound Norepinephrine Endocrinology Pituitary Gland Anterior Internal medicine Acromegaly medicine Humans Neurotransmitter Chemotherapy business.industry Middle Aged medicine.disease Growth hormone secretion medicine.anatomical_structure chemistry Growth Hormone Female business medicine.drug |
| Zdroj: | Journal of endocrinological investigation. 7(4) |
| ISSN: | 0391-4097 |
| Popis: | The effects of the noradrenergic agent Clonidine on GH secretion of the adenohypophysis were studied in 10 healthy volunteers and 11 acromegalic patients. Orally administered Clonidine led to a considerable serum human growth hormone (GH) level increase in the healthy individuals. In the acromegalic patients the Clonidine resulted in a slight, but not significant GH increase. These results support the findings that the mechanism of noradrenergic regulation of serum GH secretion is impaired in acromegaly. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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