Obsessive-Compulsive Symptoms and Other Symptoms of the At-risk Mental State for Psychosis
| Autor: | Ong, Hui Lin, Isvoranu, Adela-Maria, Schirmbeck, Frederike, McGuire, Philip, Valmaggia, Lucia, Kempton, Matthew J., van der Gaag, Mark, Riecher-Rössler, Anita, Bressan, Rodrigo A., Barrantes-Vidal, Neus, Nelson, Barnaby, Amminger, G. Paul, McGorry, Patrick, Pantelis, Christos, Krebs, Marie-Odile, Nordentoft, Merete, Glenthøj, Birte, Ruhrmann, Stephan, Sachs, Gabriele, Rutten, Bart P. F., van Os, Jim, de Haan, Lieuwe, Borsboom, Denny, Calem, Maria, Tognin, Stefania, Modinos, Gemma, Pisani, Sara, Hedges, Emily, Velthorst, Eva, Kraan, Tamar C., van Dam, Daniella S., Burger, Nadine, Politis, Athena, Goodall, Joanne, Borgwardt, Stefan, Studerus, Erich, Gadelha, Ary, Brietzke, Elisa, Asevedo, Graccielle, Asevedo, Elson, Zugman, Andre, Domínguez-Martínez, Tecelli, Monsonet, Manel, Hinojosa, Lidia, Racioppi, Anna, Kwapil, Thomas R., Kazes, Mathilde, Daban, Claire, Bourgin, Julie, Gay, Olivier, Mam-Lam-Fook, C. lia, Nordholm, Dorte, Randers, Lasse, Krakauer, Kristine, Glenthøj, Louise Birkedal, Gebhard, Dominika, Arnhold, Julia, Klosterkötter, Joachim, Lasser, Iris, Winklbaur, Bernadette, Delespaul, Philippe A. |
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| Přispěvatelé: | University of Amsterdam [Amsterdam] (UvA), Arkin Institute for Mental Health [Amsterdam, The Netherlands] (AIMH), King‘s College London, Vrije Universiteit Amsterdam [Amsterdam] (VU), Universitätsspital Basel [Switzerland], Universidade Federal de São Paulo, Universitat Autònoma de Barcelona (UAB), Centro de Investigación Biomédica en Red Salud Mental [Madrid] (CIBER-SAM), University of Melbourne, Institut de psychiatrie et neurosciences de Paris (IPNP - U1266 Inserm), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP), University of Copenhagen = Københavns Universitet (KU), University of Cologne, Medizinische Universität Wien = Medical University of Vienna, Maastricht University Medical Centre (MUMC), Maastricht University [Maastricht], Utrecht University [Utrecht], EU-GEI High Risk Study: Maria Calem, Stefania Tognin, Gemma Modinos, Sara Pisani, Emily Hedges, Eva Velthorst, Tamar C Kraan, Daniella S van Dam, Nadine Burger, Athena Politis, Joanne Goodall, Stefan Borgwardt, Erich Studerus, Ary Gadelha, Elisa Brietzke, Graccielle Asevedo, Elson Asevedo, Andre Zugman, Tecelli Domínguez-Martínez, Manel Monsonet, Lidia Hinojosa, Anna Racioppi, Thomas R Kwapil, Mathilde Kazes, Claire Daban, Julie Bourgin, Olivier Gay, Célia Mam-Lam-Fook, Dorte Nordholm, Lasse Randers, Kristine Krakauer, Louise Birkedal Glenthøj, Dominika Gebhard, Julia Arnhold, Joachim Klosterkötter, Iris Lasser, Bernadette Winklbaur, Philippe A Delespaul, Adult Psychiatry, ANS - Mood, Anxiety, Psychosis, Stress & Sleep, APH - Mental Health, ANS - Complex Trait Genetics, Psychologische Methodenleer (Psychologie, FMG), Clinical Psychology, RS: MHeNs - R3 - Neuroscience, Psychiatrie & Neuropsychologie, MUMC+: MA Psychiatrie (3), RS: MHeNs - R2 - Mental Health, Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), University of Copenhagen = Københavns Universitet (UCPH), Martinez Rico, Clara |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Male
DISORDER Obsessive-Compulsive Disorder Ultra-high risk obsessive-compulsive Psychological intervention clinical high risk Anxiety 0302 clinical medicine SCHIZOPHRENIA COMPREHENSIVE ASSESSMENT psychosis Social isolation network analysis Depression (differential diagnoses) ASSOCIATIONS Psychiatry [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology Obsessive-compulsive Depression Clinical high risk anxiety CHILDHOOD TRAUMA Psychiatry and Mental health Schizophrenia depression Blunted Affect Female Network analysis medicine.symptom Life Sciences & Biomedicine Clinical psychology Adult Psychosis AcademicSubjects/MED00810 Risk Assessment ultra-high risk 03 medical and health sciences Young Adult medicine Humans METAANALYSIS VULNERABILITY SPECTRUM Science & Technology business.industry At risk mental state medicine.disease 030227 psychiatry INDIVIDUALS Psychotic Disorders Case-Control Studies business 030217 neurology & neurosurgery [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology Regular Articles |
| Zdroj: | Schizophrenia Bulletin Schizophrenia Bulletin, Oxford University Press (OUP), 2021, pp.sbaa187. ⟨10.1093/schbul/sbaa187⟩ EU-GEI High Risk Study 2021, ' Obsessive-Compulsive Symptoms and Other Symptoms of the At-risk Mental State for Psychosis: A Network Perspective ', Schizophrenia Bulletin, vol. 47, no. 4, pp. 1018-1028 . https://doi.org/10.1093/schbul/sbaa187 Schizophrenia bulletin, 47(4), 1018-1028. Oxford University Press Schizophrenia Bulletin, 47(4), 1018-1028. Oxford University Press Ong, H L, Isvoranu, A-M, Schirmbeck, F, McGuire, P, Valmaggia, L, Kempton, M J, Van Der Gaag, M, Riecher-Rössler, A, Bressan, R A, Barrantes-Vidal, N, Nelson, B, Amminger, G P, McGorry, P, Pantelis, C, Krebs, M-O, Nordentoft, M, Glenthøj, B, Ruhrmann, S, Sachs, G, Rutten, B P F, Van Os, J, De Haan, L, Borsboom, D, Calem, M, Tognin, S, Modinos, G, Pisani, S, Hedges, E, Velthorst, E, Kraan, T C, Van Dam, D S, Burger, N, Politis, A, Goodall, J, Borgwardt, S, Studerus, E, Gadelha, A, Brietzke, E, Asevedo, G, Asevedo, E, Zugman, A, Domínguez-Martínez, T, Monsonet, M, Hinojosa, L, Racioppi, A, Kwapil, T R, Kazes, M, Daban, C, Bourgin, J, Gay, O, Mam-Lam-Fook, C, Nordholm, D, Randers, L, Krakauer, K, Glenthøj, L B, Gebhard, D, Arnhold, J, Klosterkötter, J, Lasser, I, Winklbaur, B & Delespaul, P A 2021, ' Obsessive-Compulsive Symptoms and Other Symptoms of the At-risk Mental State for Psychosis : A Network Perspective ', Schizophrenia bulletin, vol. 47, no. 4, pp. 1018-1028 . https://doi.org/10.1093/schbul/sbaa187 |
| ISSN: | 1745-1701 0586-7614 |
| Popis: | Background The high prevalence of obsessive-compulsive symptoms (OCS) among subjects at Ultra-High Risk (UHR) for psychosis is well documented. However, the network structure spanning the relations between OCS and symptoms of the at risk mental state for psychosis as assessed with the Comprehensive Assessment of At Risk Mental States (CAARMS) has not yet been investigated. This article aimed to use a network approach to investigate the associations between OCS and CAARMS symptoms in a large sample of individuals with different levels of risk for psychosis. Method Three hundred and forty-one UHR and 66 healthy participants were included, who participated in the EU-GEI study. Data analysis consisted of constructing a network of CAARMS symptoms, investigating central items in the network, and identifying the shortest pathways between OCS and positive symptoms. Results Strong associations between OCS and anxiety, social isolation and blunted affect were identified. Depression was the most central symptom in terms of the number of connections, and anxiety was a key item in bridging OCS to other symptoms. Shortest paths between OCS and positive symptoms revealed that unusual thought content and perceptual abnormalities were connected mainly via anxiety, while disorganized speech was connected via blunted affect and cognitive change. Conclusions Findings provide valuable insight into the central role of depression and the potential connective component of anxiety between OCS and other symptoms of the network. Interventions specifically aimed to reduce affective symptoms might be crucial for the development and prospective course of symptom co-occurrence. |
| Databáze: | OpenAIRE |
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