Results of molecular diagnostic assays targeting feline herpesvirus-1 and feline calicivirus in adult cats administered modified live vaccines
| Autor: | Jennifer R. Hawley, Julia K. Veir, Rebecca Ruch-Gallie, Michael R. Lappin |
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| Rok vydání: | 2011 |
| Předmět: |
Male
Feline Panleukopenia Pilot Projects Antibodies Viral Cat Diseases Polymerase Chain Reaction Random Allocation Animals Medicine Varicellovirus Small Animals Respiratory Tract Infections Caliciviridae Infections Feline calicivirus CATS biology business.industry Viral Vaccine Calicivirus Viral Vaccines Herpesviridae Infections biology.organism_classification Virology Vaccination Nasal Mucosa Cats biology.protein Pharynx RNA Viral Female Nasal administration Feline herpesvirus Feline Panleukopenia Virus Antibody business Calicivirus Feline |
| Zdroj: | Journal of Feline Medicine and Surgery. 13:541-545 |
| ISSN: | 1532-2750 1098-612X |
| Popis: | In this pilot study, 12 adult, gang-housed cats that were known to be previously exposed ( n=12) to feline herpesvirus-1 (FHV-1) and/or vaccinated against ( n=2) feline calicivirus (FCV) and FHV-1 were randomly assigned to one of two groups of six cats each. Nasal and pharyngeal samples were collected from each cat on days −7, −3, and 0 prior to vaccination and on days 3, 7, 10, 14, 17, 21, and 28 after vaccination with an FHV-1, FCV, and panleukopenia (FVRCP) vaccine developed for intranasal (six cats) or parenteral (six cats) use. FHV-1 DNA was amplified from 1/12 cats (1/69 samples; 1.4%) prior to vaccination and 2/12 cats after vaccination (2/154 samples; 1.3%). FCV RNA was amplified from 2/12 cats (2/69 samples; 2.9%) prior to vaccination and 7/12 cats (12/154 samples; 7.8%) after vaccination. Positive molecular diagnostic assay results for FHV-1 and FCV were uncommon prior to or after vaccination in these cats. |
| Databáze: | OpenAIRE |
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