Clinical Analysis of Phyllodes Tumor of the Breast

Autor:	Dong Bock Shin, Seung Yun Ha, Sang Hoon Han, Kyung Ho Cha, Tae Hoon Lee, Heung Gyu Park, Woon Gi Lee
Rok vydání:	2001
Předmět:	Cancer Research medicine.medical_specialty Scintimammography Clinical pathology medicine.diagnostic_test business.industry Axillary Lymph Node Dissection Phyllodes tumor medicine.disease Benign tumor Oncology Biopsy medicine Mammography Radiology Medical diagnosis business
Zdroj:	Cancer Research and Treatment. 33:458-462
ISSN:	2005-9256 1598-2998
DOI:	10.4143/crt.2001.33.6.458
Popis:	PURPOSE Phyllodes tumors are fibroepithelial mammary lesions that tend to behave in a benign fashion but may undergo sarcomatous transformation. They account for 0.3 to 0.5 percent of all breast tumors. Their behavior is not well understood by many clinicians. MATERIALS AND METHODS We retrospectively reviewed the clinical, radiologic, and pathologic finding and treatment modality of 31 patients of phyllodes tumor diagnosed at the Breast Clinic, Gachon Medical School Gil Medical Center between July 1992 and July 2000. RESULTS Pathologically, 6 patients (19.3%) had malignant tumor and 25 patients (80.7%) had benign lesions. All were women with average age of 36 years. The patients with malignant tumors tended to be older and had larger tumors and shorter duration. For preoperative diagnosis, we used mammography, sonography, and MIBI Scintimammography, fine needle aspiration cytology and biopsy. All these diagnostic methods suggested the diagnosis of phyllodes tumors in only 8 cases (26%). All patients received surgical treatment: excision in 21 cases, wide excision in 3 cases, simple mastectomy in 5 cases, and simple mastectomy with axillary lymph node dissection 2 cases. One patient with malignant tumor, two patients with borderline tumor and three patients with benign tumor experienced recurrence (19.3%). CONCLUSION None of the clinical or radiologic characteristics was useful in predicting for phyllodes tumor. Phyllodes tumors were difficult to make proper preoperative diagnoses and to differ malignant tumor from a benign one. This led to a simple excision and resulted in high local recurrence. We suggest that the initial or subsequent wide excision is an appropriate surgery to decrease the recurrence.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99166d71b4f0df9248a6efc6e3bf759f https://doi.org/10.4143/crt.2001.33.6.458 Zobrazit plný text záznamu