The Role of Apolipoprotein (A) In Pathogenesis and Clinical Course of Deep Venous Thrombosis
| Autor: | Marek Chrapko, Tomasz Zubilewicz, Adam Skwarzyński, Wacław Karakuła |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Adult
Male medicine.medical_specialty Apolipoprotein B medicine.medical_treatment Physical examination Apoprotein(a) Gastroenterology Fibrin Fibrinogen Degradation Products Pathogenesis Risk Factors Internal medicine Fibrinolysis medicine Humans Aged Retrospective Studies Aged 80 and over Venous Thrombosis biology medicine.diagnostic_test business.industry Widespread Disease General Medicine Middle Aged medicine.disease Pulmonary embolism Venous thrombosis biology.protein Etiology Female Surgery business Biomarkers |
| Zdroj: | Polish Journal of Surgery. 86 |
| ISSN: | 0032-373X |
| DOI: | 10.2478/pjs-2014-0092 |
| Popis: | Deep venous thrombosis is widespread disease, which complications, like: pulmonary embolism and postphlebitis syndrome areimportant social problem. There are many well-known and accurately described risk factors, though in many cases etiology remains unexplained. Further research into causes of deep venous thrombosis seem to be fully justified.was the evaluation of the influence of apolipoprotein (a) serum level in patients with deep venous thrombosis and the changes of its concentration during the treatment.26 patients with newly diagnosed deep venous thrombosis (DVT) were enrolled to the study. Diagnosis of DVT was established by use of physical examination and duplex Doppler. Measurements of apolipoprotein (a) and D-dimers serum level were recorded on the following days, starting from the day of the initial diagnosis: 1, 7, 14 and 84.Statistically significant increase of the level of serum apolipoprotein (a) has been found during properly conducted treatment.Alterations of the concentration of serum apoliprotein (a) during the deep venous thrombosis treatment, indicates the involvement of apolipoprotein (a) in pathogenesis of deep venous thrombosis. |
| Databáze: | OpenAIRE |
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