Highly active antiretroviral therapy and cervical cytologic abnormalities among women with HIV infection in a limited-resource setting
| Autor: | Joseph O. Ugboaja, Charlotte Blanche Oguejiofor, Onyecherelam M. Ogelle |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
medicine.medical_specialty Multivariate analysis HIV diagnosis Human immunodeficiency virus (HIV) Nigeria HIV Infections Cervix Uteri medicine.disease_cause Logistic regression Young Adult 03 medical and health sciences 0302 clinical medicine Antiretroviral Therapy Highly Active Internal medicine Cytology medicine Humans Prospective Studies 030212 general & internal medicine Prospective cohort study Poverty Vaginal Smears Gynecology 030219 obstetrics & reproductive medicine business.industry Obstetrics and Gynecology General Medicine Middle Aged Antiretroviral therapy CD4 Lymphocyte Count Cross-Sectional Studies Female business Limited resources |
| Zdroj: | International Journal of Gynecology & Obstetrics. 140:228-232 |
| ISSN: | 0020-7292 |
| Popis: | Objective To examine the relationship between highly active antiretroviral therapy (HAART) and cervical cytologic abnormalities among women with HIV infection. Methods A cross-sectional prospective study was undertaken of 110 women attending an HIV clinic in Nnewi, Nigeria, between January 2016 and January 2017. A cervical smear was obtained. A bivariate analysis was undertaken, and multiple logistic regression models were used to identify factors independently associated with cervical cytologic analysis. Results Cervical cytologic abnormalities were identified in 31 (28.2%) participants. On bivariate analysis, use of HAART for 2–5 years was associated with a reduction in the risk of cervical cytologic abnormalities (P=0.033), and this risk was further reduced when HAART was taken for more than 5 years (P |
| Databáze: | OpenAIRE |
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