99mTc labeling white blood cells with a simple technique: Clinical application
| Autor: | Marcos Pinto Pellini, Maria Garděnia Evangelista, Mario Bernardo-Filho, Bianca Gutfilen, Sérgio Roberto Fernandes, Jacqueline de Roure e Neder, José Luiz Medeiros de Amarante |
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| Rok vydání: | 1994 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Adolescent Organotechnetium Compounds chemistry.chemical_element Technetium Technetium Tc 99m Exametazime hemic and lymphatic diseases Oximes Leukocytes medicine Humans Radiology Nuclear Medicine and imaging Radionuclide imaging In patient Radionuclide Imaging business.industry Osteomyelitis General Medicine Middle Aged medicine.disease chemistry Isotope Labeling Female business circulatory and respiratory physiology |
| Zdroj: | Annals of Nuclear Medicine. 8:85-89 |
| ISSN: | 1864-6433 0914-7187 |
| Popis: | Several radionuclides and different methods have been employed as cellular labels to study inflammatory sites in man. Here we present the results obtained with white blood cells (WBC) labeled with 99mTc using a simple and low cost new technique (SnTec). WBC were incubated with 12 micrograms/ml of stannous chloride for 10 min at room temperature. Then 99mTc was added. After 10 min, the 99mTc-labeled WBC were washed and injected into the patient. Comparison studies with 99mTc-labeled WBC using the HMPAO technique were carried out in patients with suspected osteomyelitis. Since the results are similar with both methods, we suggest the use of SnTec to label WBC, in cases of inflammatory diseases. |
| Databáze: | OpenAIRE |
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