Autologous gastro-intestinal reconstruction: the composite ileo-colic loop
| Autor: | I. D. Ward, A. Bianchi, M. Lendon |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
medicine.medical_specialty
business.industry medicine.medical_treatment In vivo absorption Ileum General Medicine Short bowel syndrome medicine.disease Gastroenterology digestive system diseases medicine.anatomical_structure Internal medicine Laparotomy Pediatrics Perinatology and Child Health medicine Surgery Mesentery business Gastro intestinal Ileal mucosa Peristalsis |
| Zdroj: | Pediatric Surgery International. 11:248-251 |
| ISSN: | 1437-9813 0179-0358 |
| Popis: | A reproducible technique was developed experimentally in pigs for construction of a 'composite bowel tube' (CBT) made up of ileal mucosa that was grafted to a mucosally denuded colonic muscle surface vascularised by the colonic mesentery. Macroscopic and microscopic studies at terminal laparotomy revealed a viable, mucosally lined, patent peristaltic loop of bowel in six of the eight animals. Two animals died after sloughing the grafted mucosa. In vivo absorption studies, using l-alanine as an index of amino acid absorption, showed a transport pattern through the grafted mucosa of the composite ileo-colic loop appropriate to ileum when compared with controls. The CBT constitutes another autologous gastro-intestinal reconstructive technique for redistribution of available absorptive mucosa over a longer intestinal length, and may therefore be of benefit in the management of the short-bowel syndrome. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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