Age at diagnosis and loss of heterozygosity on chromosome 1p and 19q in oligodendroglial tumors
| Autor: | H. Landolt, Erik Vassella, M. Moschopulos, H. Laeng, Andreas R. Huber, U. Roelcke, Christine Murtin, Luigi Mariani, Martin Hergersberg, Joachim Weis |
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| Rok vydání: | 2006 |
| Předmět: |
Adult
Male Aging Cancer Research Pathology medicine.medical_specialty Oligoastrocytoma endocrine system diseases Oligodendroglioma Loss of Heterozygosity Age at diagnosis Biology Central nervous system disease Loss of heterozygosity O(6)-Methylguanine-DNA Methyltransferase medicine Humans Oligodendroglial Tumor Age of Onset neoplasms Brain Neoplasms Incidence (epidemiology) Chromosome Middle Aged medicine.disease digestive system diseases stomatognathic diseases Neurology Oncology Chromosomes Human Pair 1 Female Neurology (clinical) Chromosomes Human Pair 19 |
| Zdroj: | Hergersberg, M; Mariani, L; Vassella, E; Murtin, C; Weis, J; Moschopulos, M; Laeng, H; Landolt, H; Huber, A; Roelcke, U (2006). Age at diagnosis and loss of heterozygosity on chromosome 1p and 19q in oligodendroglial tumors. Journal of neuro-oncology, 80(2), pp. 215-7. Boston, Mass.: Springer 10.1007/s11060-006-9177-2 |
| ISSN: | 1573-7373 0167-594X |
| DOI: | 10.1007/s11060-006-9177-2 |
| Popis: | The age distribution and incidence of loss of heterozygosity (LOH) of 1p and 19q was analyzed in 85 oligodendroglial tumors WHO II and III. The peak of tumor manifestation was in the age group of 35 to 55 years. There was no association between age at diagnosis and LOH incidence. We conclude that the prognostic effect of age on survival is not mediated by LOH 1p/19q. |
| Databáze: | OpenAIRE |
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