Does Surgically Induced Weight Loss Improve Daytime Sleepiness?
| Autor: | Paul T. Cirangle, Dena M. Bravata, Neeta Parimi, Jon-Erik C Holty, Gregg H. Jossart, Michael Ballesteros, Terri Blackwell, Katie L. Stone, Nicole D. Kimbrough, Jennifer M. Rose |
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| Rok vydání: | 2010 |
| Předmět: |
Adult
Male medicine.medical_specialty Endocrinology Diabetes and Metabolism medicine.medical_treatment Bariatric Surgery Excessive daytime sleepiness Disorders of Excessive Somnolence Quality of life Weight loss Weight Loss Positive airway pressure medicine Humans Prospective Studies Prospective cohort study Nutrition and Dietetics business.industry Epworth Sleepiness Scale Middle Aged Obesity Morbid Surgery Anesthesia Quality of Life Female Gastrectomy medicine.symptom business Body mass index |
| Zdroj: | Obesity Surgery. 21:1535-1545 |
| ISSN: | 1708-0428 0960-8923 |
| DOI: | 10.1007/s11695-010-0213-0 |
| Popis: | Morbid obesity is associated with excessive daytime sleepiness and reduced health-related quality of life. We prospectively evaluated the pre- and postoperative responses of bariatric surgery recipients with the Epworth Sleepiness Scale (ESS) and the Short Form-12. Participants (n = 223; 79% women) with a mean body mass index (BMI) and ESS of 44.8 ± 7.9 kg/m2 and 7.9 ± 4.5, respectively, received a vertical gastrectomy (76%) or Roux-en-Y gastric bypass (12%). Preoperatively, 30% of patients complained of excessive daytime sleepiness (ESS > 10). Patients with preoperative excessive daytime sleepiness were more obese (p = 0.002), had higher fasting glucose levels (p = 0.02), more likely to have a diagnosis of sleep-disordered breathing (p < 0.001), report snoring (p < 0.001), and had lower health-related quality of life measures particularly physical function (p < 0.001), depression (p = 0.006), and sexual satisfaction (p = 0.04) than non-sleepy patients. At 12-months postoperatively, most patients experienced a significant reduction in BMI (28.6 ± 5.5 kg/m2, p < 0.001) and excessive daytime sleepiness (mean ESS 5.3 ± 3.3, p < 0.001). Patients with a clinically relevant improvement in the ESS at 12-months post-operatively had greater improvements in physical function (p = 0.009) and snoring (p = 0.010) and were more likely still using positive airway pressure therapy (p = 0.032) than patients without a clinically relevant improvement. Statistically and clinically significant improvements in all health-related quality of life measures were noted at 24 months. Bariatric surgery is associated with dramatic weight loss and improvements in physical functioning and daytime sleepiness. |
| Databáze: | OpenAIRE |
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