Rationale and Design for the Diabetes RElated to Acute Pancreatitis and Its Mechanisms Study
| Autor: | Phil A, Hart, Georgios I, Papachristou, Walter G, Park, Anne-Marie, Dyer, Vernon M, Chinchilli, Elham, Afghani, Venkata S, Akshintala, Dana K, Andersen, James L, Buxbaum, Darwin L, Conwell, Kathleen M, Dungan, Jeffrey J, Easler, Evan L, Fogel, Carla J, Greenbaum, Rita R, Kalyani, Murray, Korc, Richard, Kozarek, Maren R, Laughlin, Peter J, Lee, Jennifer L, Maranki, Stephen J, Pandol, Anna Evans, Phillips, Jose, Serrano, Vikesh K, Singh, Cate, Speake, Temel, Tirkes, Frederico G S, Toledo, Guru, Trikudanathan, Santhi Swaroop, Vege, Ming, Wang, Cemal, Yazici, Atif, Zaheer, Christopher E, Forsmark, Melena D, Bellin, Dhiraj, Yadav |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Pancreas |
| ISSN: | 1536-4828 0885-3177 |
| Popis: | Acute pancreatitis (AP) is a disease characterized by an acute inflammatory phase followed by a convalescent phase. Diabetes mellitus (DM) was historically felt to be a transient phenomenon related to acute inflammation; however, it is increasingly recognized as an important late and chronic complication. There are several challenges that have prevented precisely determining the incidence rate of DM following AP and understanding the underlying mechanisms. The Diabetes RElated to Acute Pancreatitis and its Mechanisms (DREAM) Study is a prospective cohort study designed to address these and other knowledge gaps to provide the evidence needed to screen for, prevent, and treat DM following AP. In the following article, we summarize literature regarding the epidemiology of DM following AP, and provide the rationale and an overview of the DREAM study. |
| Databáze: | OpenAIRE |
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