Fibronectin glomerulopathy in a 34-year-old man : a case report

Autor:	Mario Ćorić, Luka Brčić, Marijana Ćorić, Duško Kuzmanić, Iva Brcic
Jazyk:	angličtina
Rok vydání:	2010
Předmět:	Adult Male Pathology medicine.medical_specialty Kidney Glomerulus Fibronectin glomerulopathy Renal function urologic and male genital diseases Pathology and Forensic Medicine Microscopy Electron Transmission Structural Biology Glomerulopathy Internal medicine medicine Humans Microscopic hematuria Hematuria Proteinuria biology medicine.diagnostic_test business.industry urogenital system medicine.disease female genital diseases and pregnancy complications Fibronectins Glomerular Mesangium Fibronectin Endocrinology Treatment Outcome Mesangium Hypertension biology.protein Kidney Diseases Renal biopsy electron microscopy fibronectin glomerulopathy immunofluorescence proteinuria medicine.symptom business
Popis:	Fibronectin glomerulopathy is an inherited non-immune-mediated glomerulopathy associated with the massive deposition of fibronectin. It presents with proteinuria, microscopic hematuria, and hypertension that lead to end-stage renal failure in the second to sixth decade of life. A 34-year-old male was referred with proteinuria (6 g/day), microscopic hematuria and hypertension (220/130 mmHg). Renal biopsy specimen showed massive deposits of fibronectin in the mesangium and subendothelial spaces. After 20 months of multidrug treatment his renal function is stable.
Databáze:	OpenAIRE
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