Epidemiology of Strongyloides stercoralis in northern Italy: Results of a multicentre case-control study, February 2013 to July 2014
| Autor: | Giuseppina Napoletano, Marta Mascarello, Dora Buonfrate, Matteo Bassetti, Giacomo Caramaschi, Fabrizio F. Abrescia, Novella Scattolo, Mario Giobbia, Zeno Bisoffi, Mara Baldissera, Paola Rodari |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Male Epidemiology serology Serology Feces 0302 clinical medicine 80 and over Prevalence Eosinophilia Aged 80 and over biology Middle Aged Strongyloidiasis parasitic disease Italy Regression Analysis Female medicine.symptom Research Article Adult medicine.medical_specialty Adolescent 030106 microbiology 030231 tropical medicine Antibodies Helminth Emigrants and Immigrants Enzyme-Linked Immunosorbent Assay Antibodies Strongyloides stercoralis 03 medical and health sciences Young Adult Age Distribution prevalence Virology Internal medicine medicine Helminth Animals Humans Sex Distribution Aged business.industry Public Health Environmental and Occupational Health Case-control study Odds ratio biology.organism_classification medicine.disease Confidence interval Case-Control Studies Sentinel Surveillance Immunology business |
| Zdroj: | Eurosurveillance |
| Popis: | Strongyloides stercoralis is a soil-transmitted helminth widely diffused in tropical and subtropical regions of the world. Autochthonous cases have been also diagnosed sporadically in areas of temperate climate. We aimed at defining the epidemiology of strongyloidiasis in immigrants and Italians living in three northern Italian Regions. Screening for S. stercoralis infection was done with serology, confirmation tests were a second serological method or stool agar culture. A case–control approach was adopted and patients with a peripheral eosinophil count ≥ 500/mcL were classified as cases. Of 2,701 individuals enrolled here 1,351 were cases and 1,350 controls; 86% were Italians, 48% women. Italians testing positive were in 8% (97/1,137) cases and 1% (13/1,178) controls (adjusted odds ratio (aOR) 8.2; 95% confidence interval (CI): 4.5–14.8), while positive immigrants were in 17% (36/214) cases and in 2% (3/172) controls (aOR 9.6; 95% CI: 2.9–32.4). Factors associated with a higher risk of infection for all study participants were eosinophilia (p |
| Databáze: | OpenAIRE |
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