p-synephrine induces transcriptional changes via the cAMP/PKA pathway but not cytotoxicity or mutagenicity in human gastrointestinal cells

Autor:	Alexandre Ferro Aissa, Patrick Wellington da Silva dos Santos, Carla Botelho Machado, Gustavo Rafael Mazzaron Barcelos, Diego Luis Ribeiro, Ana Rita Thomazela Machado, Lusânia Maria Greggi Antunes
Rok vydání:	2020
Předmět:	0301 basic medicine 030102 biochemistry & molecular biology Chemistry Health Toxicology and Mutagenesis Alkaloid Human gastrointestinal tract Synephrine social sciences Pharmacology Toxicology CÓLON 03 medical and health sciences 030104 developmental biology medicine.anatomical_structure Weight loss parasitic diseases medicine population characteristics medicine.symptom Cytotoxicity Micronucleus Adverse effect human activities geographic locations medicine.drug
Zdroj:	Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP
ISSN:	1087-2620 1528-7394
DOI:	10.1080/15287394.2020.1855490
Popis:	p-Synephrine (SN) is an alkaloid added to thermogenic formulations for weight loss that is predominantly absorbed in the human gastrointestinal tract (GI). As the adverse effects of SN on GI cells ...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98dfabb3e6e33421cfe1e607f97c9b83 https://doi.org/10.1080/15287394.2020.1855490 Zobrazit plný text záznamu