Childhood Obesity and Extracorporeal Membrane Oxygenation: Special Considerations for Successful Outcomes
| Autor: | Brian Reemtsen, Amit Iyengar, Reshma Biniwale, Jessica Samson, Allen Zhu |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Inotrope
medicine.medical_specialty business.industry medicine.medical_treatment Mortality rate 030204 cardiovascular system & hematology Critical Care and Intensive Care Medicine medicine.disease Obesity Childhood obesity Surgery 03 medical and health sciences 0302 clinical medicine 030228 respiratory system Anesthesia Pediatrics Perinatology and Child Health medicine Extracorporeal membrane oxygenation Lean body mass In patient business Perfusion |
| Popis: | The effects of obesity on venoarterial extracorporeal membrane oxygenation (VA-ECMO) outcomes in pediatric population are unknown. We performed retrospective analysis of 41 children (age 2–18 years) undergoing VA-ECMO. The percentage difference between actual body weight and lean body weight, referred to as Δmass, was calculated. Ratios of Δmass to ECMO flow were calculated at 4 and 24 hours. In patients with Δmass:flow ≥ 0.1 at 4 hours, higher 24-hour lactates (20.0 vs. 14.5 mg/dL; p = 0.002) and inotrope scores (17.3 vs. 11.2; p = 0.015) were observed. However, elevated Δmass:flow was not associated with mortality, and in-hospital mortality rates between groups were similar (53 vs. 45%; p = 0.647). In obese pediatric patients requiring VA-ECMO, increased flow is necessary to avoid complications of hypoperfusion and related complications. |
| Databáze: | OpenAIRE |
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