Combination of electromembrane extraction and electro-assisted liquid-liquid microextraction: A tandem sample preparation method
| Autor: | Ali Shokri, Mahnaz Nasiri-Aghdam, Turaj Rahmani, Saeed Nojavan, Hossein Shaghaghi |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Analyte
Imipramine Chromatography Gas Liquid Phase Microextraction 02 engineering and technology Wastewater 01 natural sciences Biochemistry Chemistry Techniques Analytical Analytical Chemistry Limit of Detection Humans Sample preparation Detection limit Chromatography Tandem Electromembrane extraction Chemistry 010401 analytical chemistry Organic Chemistry Extraction (chemistry) Membranes Artificial General Medicine Repeatability Electrochemical Techniques Hydrogen-Ion Concentration 021001 nanoscience & nanotechnology Antidepressive Agents 0104 chemical sciences Clomipramine Solvents Gas chromatography 0210 nano-technology |
| Zdroj: | Journal of chromatography. A. 1563 |
| ISSN: | 1873-3778 |
| Popis: | As a well-known extraction procedure, electromembrane extraction (EME) was combined with electro-assisted liquid-liquid microextraction (EA-LLME) in the present work, which resulted in a promising method. This hyphenated sample preparation method, named EME-EA-LLME, was followed by GC for the determination of two model analytes (clomipramine and imipramine). The effective parameters of both EME and EA-LLME (such as organic solvent, pH of acceptor and sample solutions, voltage and extraction time) were optimized. The proposed EME-EA-LLME procedure demonstrated good linearity with coefficients of determination, R2 ≥ 0.998 over the concentration range of 0.5–750 ng/mL. Limit of detection for both analytes was 0.15 ng/mL. The corresponding repeatability ranged from 6.9 to 12.2% (n = 3). The high enrichment factors were obtained as 770.3 and 561.4 for imipramine and clomipramine, respectively. The advantages of this tandem sample preparation method were low detection limits, simplicity, low cost, and short analysis time ( |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect