The polychloromethylation/acyloxylation of 1,6-enynes with chloroalkanes and diacyl peroxides through dual-role designs

Autor:	Jun-Hao Zhang, Li-Lin Jiang, Sen-Jie Hu, Jiao-Zhe Li, Xuan-Chi Yu, Fa-Liang Liu, Yu-Tao Guan, Ke-Wei Lei, Wen-Ting Wei
Rok vydání:	2022
Předmět:	Organic Chemistry Physical and Theoretical Chemistry Biochemistry
Zdroj:	Organic & Biomolecular Chemistry. 20:7067-7070
ISSN:	1477-0539 1477-0520
DOI:	10.1039/d2ob01330d
Popis:	The novel polychloromethylation/acyloxylation of 1,6-enynes with chloroalkanes and diacyl peroxides through dual-role designs has been developed to prepare 2-pyrrolidinone derivatives with polychloromethyl units with the use of an inexpensive copper salt under mild conditions. This strategy includes two dual-role designs, not only improving atomic utilization but also allowing a cleaner process. The wide substrate scope and simple reaction conditions demonstrate the practicability of this protocol.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98cff92129074b505f7af5b899f839fd https://doi.org/10.1039/d2ob01330d Zobrazit plný text záznamu