Left Ventricular Untwisting Rate by Speckle Tracking Echocardiography
| Autor: | Jianwen Wang, Guillermo Torre-Amione, Sherif F. Nagueh, Yong Yue, Dirar S. Khoury |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Adult
Male medicine.medical_specialty Diastole Speckle tracking echocardiography Ventricular Dysfunction Left Dogs Physiology (medical) Internal medicine Occlusion Ventricular Pressure medicine Animals Humans Aged Heart Failure Diastolic business.industry Stroke Volume Stroke volume Middle Aged Esmolol medicine.disease Echocardiography Case-Control Studies Heart failure Ventricular pressure Cardiology Female Dobutamine Cardiology and Cardiovascular Medicine business medicine.drug |
| Zdroj: | Circulation. 116:2580-2586 |
| ISSN: | 1524-4539 0009-7322 |
| DOI: | 10.1161/circulationaha.107.706770 |
| Popis: | Background— Recent studies validated the measurement of left ventricular (LV) untwisting rate (UR) by speckle tracking echocardiography. A few reports suggest that it may provide additional noninvasive insight into LV diastolic function. Methods and Results— Simultaneous echocardiographic imaging and LV pressure measurements (7F Millar catheters) were performed in 8 adult dogs. Loading conditions were altered by caval occlusion, whereas lusitropic state was changed by dobutamine and esmolol infusion. Inferior vena cava occlusion at all experimental stages (baseline, dobutamine, esmolol) led to a significant decrease ( P ≤0.01) in LV end-systolic volume (ESV) and a significant increase in UR ( P =0.03). The best relation was observed between LV UR and ESV ( r =−0.8, P P 2 =0.83, P 2 =0.71, P Conclusions— LV UR is reduced in patients with depressed EF, but not in those with diastolic dysfunction and normal EF, and is primarily determined by twist and ESV. |
| Databáze: | OpenAIRE |
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