Enzyme-linked immunosorbent assay for the diagnosis of cerebral cysticercosis
| Autor: | I N Mohammad, Heiner D, I G Kagan, B L Miller, M A Goldberg |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Microbiology (medical)
Pathology medicine.medical_specialty Pediatrics Swine Radioimmunoassay Helminthiasis Enzyme-Linked Immunosorbent Assay Disease Antibodies Immunoenzyme Techniques Taenia solium medicine Animals Humans Brain Diseases medicine.diagnostic_test Cysticercosis business.industry Brain biopsy Aseptic meningitis medicine.disease Hydrocephalus medicine.drug_formulation_ingredient business Research Article |
| Zdroj: | Journal of Clinical Microbiology. 20:775-779 |
| ISSN: | 1098-660X 0095-1137 |
| DOI: | 10.1128/jcm.20.4.775-779.1984 |
| Popis: | Central nervous system cysticercosis is common in countries where Taenia solium occurs in pigs and the level of hygiene and sanitation is low. The clinical presentation may include epileptic seizures, focal neurological deficits, hydrocephalus, or aseptic meningitis. The disease is frequently seen in California residents of Hispanic origin. It sometimes occurs in whites from homes that employ Hispanic cooks. Diagnosis is often difficult. Computerized tomography scan and brain biopsy are the most reliable diagnostic procedures, but each has its limitations. We have found that a radioimmunoassay improves our diagnostic capability, and more recently we have adapted this to an enzyme-linked immunosorbent assay that is equally sensitive and specific and, in addition, obviates the need for radioactive materials. Details of the enzyme-linked immunosorbent assay procedure and its application to the diagnosis of central nervous system cysticercosis form the basis of this report. |
| Databáze: | OpenAIRE |
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