Increased red blood cell aggregation in retinal vein occlusion
| Autor: | Agnégs Glacet-Bernard, Alain Taccoen, Meyer M. Samama, Anne Chabanel, Françloise Lelong, Gabriel Coscas |
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| Rok vydání: | 1990 |
| Předmět: |
Adult
Erythrocyte Aggregation Male medicine.medical_specialty Pathology Retinal Vein Blood viscosity chemistry.chemical_compound Risk Factors Internal medicine Retinal Vein Occlusion Occlusion medicine Coagulopathy Humans Aged Aged 80 and over business.industry Fibrinogen Retinal Blood Proteins Hematology Middle Aged medicine.disease Red blood cell medicine.anatomical_structure chemistry Circulatory system Vascular resistance Cardiology Female business |
| Zdroj: | British Journal of Haematology. 75:127-131 |
| ISSN: | 1365-2141 0007-1048 |
| DOI: | 10.1111/j.1365-2141.1990.tb02628.x |
| Popis: | Summary Reversible aggregation of red blood cells (RBC) plays an important role in determining the flow properties of blood, and is the cause of the increase in blood viscosity at low shear rates. Retinal venous circulation is characterized by the combination of a low flow state and a high vascular resistance which might severely limit its capacity to adjust to high blood viscosity. These characteristics make the venous circulation in the retina particularly dependent on haemorheological factors. To test the possibility that high RBC aggregation could predispose to the onset and development of retinal vein occlusion (RVO), RBC aggregation and disaggregation (SEFAM erythroaggregameter, France) were measured in 64 patients with RVO. Results were compared to those of a group of 64 controls, similar in age, sex, smoking habit and associated pathologies. Increased RBC aggregation was observed in 52% of the patients, and the mean values showed a highly significant elevation of RBC aggregation parameters in RVO patients (+ 14%) when compared with controls (P |
| Databáze: | OpenAIRE |
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