Proposal for the delineation of neoadjuvant target volumes in oesophageal cancer
| Autor: | Hanna Rahbek Mortensen, Lone Hoffmann, O. Nicholas, Karin Haustermans, Maaike Berbee, Melissa Thomas, Christina T. Muijs, Marianne Nordsmark, Ganesh Radhakrishna, Rebecca Bütof, Ditte Sloth Møller, Esther G.C. Troost, Philippe Nafteux, Gilles Defraene |
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| Přispěvatelé: | Damage and Repair in Cancer Development and Cancer Treatment (DARE), RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy, Radiotherapie, MUMC+: MA Radiotherapie OC (9) |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
MARGIN Consensus Esophageal Neoplasms SURGERY IMPACT Planning target volume 030218 nuclear medicine & medical imaging 03 medical and health sciences CHEMORADIATION 0302 clinical medicine RADIATION-THERAPY medicine Humans Radiology Nuclear Medicine and imaging Medical physics RECURRENCE Observer Variation business.industry Radiotherapy Planning Computer-Assisted Oesophageal cancer Proposal for delineation Radiation Oncologists Cancer Hematology medicine.disease Neoadjuvant Therapy Neoadjuvant chemoradiation Clinical trial Clinical Practice INTENSITY-MODULATED RADIOTHERAPY Oncology 030220 oncology & carcinogenesis SURVIVAL SQUAMOUS-CELL CARCINOMA business Delineation atlas PREOPERATIVE CHEMORADIOTHERAPY |
| Zdroj: | Radiotherapy and Oncology, 156, 102-112. ELSEVIER IRELAND LTD Thomas, M, Mortensen, H R, Hoffmann, L, Møller, D S, Troost, E G C, Muijs, C T, Berbee, M, Bütof, R, Nicholas, O, Radhakrishna, G, Defraene, G, Nafteux, P, Nordsmark, M & Haustermans, K 2021, ' Proposal for the delineation of neoadjuvant target volumes in oesophageal cancer ', Radiotherapy and Oncology, vol. 156, pp. 102-112 . https://doi.org/10.1016/j.radonc.2020.11.032 Radiotherapy and Oncology 156(2021), 102-112 Radiotherapy and Oncology, 156, 102-112. Elsevier Ireland Ltd |
| ISSN: | 0167-8140 |
| DOI: | 10.1016/j.radonc.2020.11.032 |
| Popis: | PURPOSE: To define instructions for delineation of target volumes in the neoadjuvant setting in oesophageal cancer. MATERIALS AND METHODS: Radiation oncologists of five European centres participated in the following consensus process: [1] revision of published (MEDLINE) and national/institutional delineation guidelines; [2] first delineation round of five cases (patient 1-5) according to national/institutional guidelines; [3] consensus meeting to discuss the results of step 1 and 2, followed by a target volume delineation proposal; [4] circulation of proposed instructions for target volume delineation and atlas for feedback; [5] second delineation round of five new cases (patient 6-10) to peer review and validate (two additional centres) the agreed delineation guidelines and atlas; [6] final consensus on the delineation guidelines depicted in an atlas. Target volumes of the delineation rounds were compared between centres by Dice similarity coefficient (DSC) and maximum/mean undirected Hausdorff distances (Hmax/Hmean). RESULTS: In the first delineation round, the consistency between centres was moderate (CTVtotal: DSC = 0.59-0.88; Hmean = 0.2-0.4 cm). Delineations in the second round were much more consistent. Lowest variability was obtained between centres participating in the consensus meeting (CTVtotal: DSC: p |
| Databáze: | OpenAIRE |
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