Data on the Quantification of Aspartate, GABA and Glutamine Levels in the Spinal Cord of Larval Sea Lampreys after a Complete Spinal Cord Injury
| Autor: | María Celina Rodicio, Anunciación Lafuente, Blanca Fernández-López, Natividad Pereiro, Antón Barreiro-Iglesias |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Information Systems and Management Neurotransmitter systems Biology Bibliography. Library science. Information resources 03 medical and health sciences GABA 0302 clinical medicine Spinal cord transection Statistical analyses Internal medicine medicine Spinal cord injury 030304 developmental biology Sea lampreys 0303 health sciences aspartate lampreys Spinal cord medicine.disease spinal cord injury Computer Science Applications Glutamine medicine.anatomical_structure Endocrinology glutamine HPLC 030217 neurology & neurosurgery Information Systems |
| Zdroj: | Data, Vol 6, Iss 54, p 54 (2021) |
| ISSN: | 2306-5729 |
| Popis: | We used high-performance liquid chromatography (HPLC) methods to quantify aspartate, GABA, and glutamine levels in the spinal cord of larval sea lampreys following a complete spinal cord injury. Mature larval sea lampreys recover spontaneously from a complete spinal cord transection and the changes in neurotransmitter systems after spinal cord injury might be related to their amazing regenerative capabilities. The data presented here show the concentration of the aminoacidergic neurotransmitters GABA (and its precursor glutamine) and aspartate in the spinal cord of control (non-injured) and 2-, 4-, and 10-week post-lesion animals. Statistical analyses showed that GABA and aspartate levels significantly increase in the spinal cord four weeks after a complete spinal cord injury and that glutamine levels decrease 10 weeks after injury as compared to controls. These data might be of interest to those studying the role of neurotransmitters and neuromodulators in recovery from spinal cord injury in vertebrates. |
| Databáze: | OpenAIRE |
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