Recurrent malignant glioma: detection with131I labeled monoclonal antibody G-22, positron emission tomography and magnetic resonance imaging
| Autor: | Jun Yoshida, Masanori Tadokoro, Toshihiko Wakabayashi, Kengo Ito, Sadayuki Sakuma, Motoo Oshima, Takashi Kato |
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| Rok vydání: | 1993 |
| Předmět: |
Male
medicine.drug_class Scintigraphy Monoclonal antibody Iodine Radioisotopes Fluorodeoxyglucose PET Glioma medicine Humans Radiology Nuclear Medicine and imaging medicine.diagnostic_test business.industry Magnetic resonance imaging General Medicine Middle Aged medicine.disease Magnetic Resonance Imaging Radioimmunodetection Positron emission tomography Spin echo Neoplasm Recurrence Local Nuclear medicine business Tomography Emission-Computed Glioblastoma |
| Zdroj: | Annals of Nuclear Medicine. 7:119-122 |
| ISSN: | 1864-6433 0914-7187 |
| DOI: | 10.1007/bf03164577 |
| Popis: | A 45-year-old man with suspected recurrent malignant glioma was evaluated by magnetic resonance imaging (MRI), positron emission tomography (PET) and 131I labeled monoclonal antibody G-22 (G-22) scan. Following Gadolinium-DTPA, a TI-weighted spin echo image (TR 500 msec, TE 20 msec) demonstrated a large mass with an irregular margin in the left temporo-parietal area. An 18F labeled fluorodeoxyglucose PET study demonstrated marked accumulations in the left temporo-parietal area. Serial 131I-G-22 scintigraphy was obtained for a week after the injection. The uptake was most increased on the 2nd day after the injection. 131I G-22 was specific for tumor-associated antigens. |
| Databáze: | OpenAIRE |
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