A review: Roles of carbohydrates in human diseases through regulation of imbalanced intestinal microbiota
Autor: | Zhigang Zhang, Cheng Xue, Hongtao Liu, Wen-Liang Lv, Hui Xia, Junping Zheng, Aizhen Lin, Qing-Hua Gao |
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Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
0301 basic medicine
Glycolipid metabolism Carbohydrates Medicine (miscellaneous) Metabolic disease Gut microbiota Gut flora digestive system Microbiology 03 medical and health sciences Human health 0404 agricultural biotechnology medicine TX341-641 030109 nutrition & dietetics Nutrition and Dietetics biology Mechanism (biology) Nutrition. Foods and food supply Neurodegeneration 04 agricultural and veterinary sciences biology.organism_classification medicine.disease 040401 food science Colorectal cancer Prebiotics Degradation reaction Food Science |
Zdroj: | Journal of Functional Foods, Vol 74, Iss, Pp 104197-(2020) |
ISSN: | 1756-4646 |
Popis: | Gut microbiota plays a key role in the maintenance of human health. In most cases, carbohydrates can be fermented by gut microbiota as substrates. By such degradation reaction, the abundances, activities and metabolite production of gut microbiota will be regulated and thus prevent the occurrence of human diseases such as glycolipid metabolism disorders, enteric abnormality, aging and neurodegeneration, cancers and depression. In this paper, we reviewed the roles of carbohydrates in promoting human health through gut microbial regulation, as well as further studies on the regulatory mechanism and potential application of carbohydrates, which need to be strengthened in the future. |
Databáze: | OpenAIRE |
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