A Pathway to Precision Medicine for Aboriginal Australians: A Study Protocol
| Autor: | Jack Nunn, Debbie McCowen, Marcel E. Dinger, Jayden Potter, Alex Brown, Cliff J Meldrum, John Skinner, Yeu-Yao (Kevin) Cheng, Sandra T. Cooper, Boe Rambaldini, Tom Calma, Kylie Gwynne, Kerry Faires, Tiffany Boughtwood, Jennifer A. Byrne |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
QH301-705.5 Advisory committee Endocrinology Diabetes and Metabolism precision medicine Participatory action research Aboriginal health Health outcomes Aboriginal and Torres Strait Islanders Biochemistry Genetics and Molecular Biology (miscellaneous) Biochemistry 03 medical and health sciences 0302 clinical medicine Endocrinology Structural Biology Health care Protocol Genetics genomics 030212 general & internal medicine Sociology Biology (General) Molecular Biology Uncategorized Protocol (science) Medical education Australian business.industry Corporate governance personalised medicine Precision medicine 030104 developmental biology Torres strait General partnership co-design participatory research business Biotechnology Qualitative research |
| Zdroj: | Methods and Protocols, Vol 4, Iss 42, p 42 (2021) Methods and Protocols |
| ISSN: | 2409-9279 |
| Popis: | (1) Background: Genomic precision medicine (PM) utilises people’s genomic data to inform the delivery of preventive and therapeutic health care. PM has not been well-established for use with people of Aboriginal and Torres Strait Islander ancestry due to the paucity of genomic data from these communities. We report the development of a new protocol using co-design methods to enhance the potential use of PM for Aboriginal Australians. (2) Methods: This iterative qualitative study consists of five main phases. Phase-I will ensure appropriate governance of the project and establishment of a Project Advisory Committee. Following an initial consultation with the Aboriginal community, Phase-II will invite community members to participate in co-design workshops. In Phase-III, the Chief Investigators will participate in co-design workshops and document generated ideas. The notes shall be analysed thematically in Phase-IV with Aboriginal community representatives, and the summary will be disseminated to the communities. In Phase-V, we will evaluate the co-design process and adapt our protocol for the use in partnership with other communities. (3) Discussion: This study protocol represents a crucial first step to ensure that PM research is relevant and acceptable to Aboriginal Australians. Without fair access to PM, the gap in health outcome between Aboriginal and non-Aboriginal Australians will continue to widen. |
| Databáze: | OpenAIRE |
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