Life expectancy with chronic kidney disease: an educational review

Autor: Guy H. Neild
Rok vydání: 2015
Předmět:
Nephrology
Adult
Male
medicine.medical_specialty
Adolescent
Life expectancy
medicine.medical_treatment
030232 urology & nephrology
Renal function
Disease
030204 cardiovascular system & hematology
urologic and male genital diseases
Progressive renal failure
03 medical and health sciences
Young Adult
0302 clinical medicine
Renal Dialysis
Risk Factors
Internal medicine
Chronic kidney disease
Medicine
Humans
Pediatrics
Perinatology
and Child Health
Renal replacement therapy
Renal Insufficiency
Chronic
Intensive care medicine
Child
Dialysis
CAKUT
Educational Review
Kidney
business.industry
Age Factors
End-stage kidney disease
medicine.disease
Creatine
medicine.anatomical_structure
Cardiovascular Diseases
Pediatrics
Perinatology and Child Health
Female
business
Kidney disease
Glomerular Filtration Rate
Zdroj: Pediatric Nephrology (Berlin, Germany)
ISSN: 1432-198X
Popis: Can renal prognosis and life expectancy be accurately predicted? Increasingly, the answer is yes. The natural history of different forms of renal disease is becoming clearer; the degree of reduction in glomerular filtration rate (GFR) and the magnitude of proteinuria are strong predictors of renal outcome. Actuarial data on life expectancy from the start of renal replacement therapy are available from renal registries such as the U.S. Renal Data System (USRDS), and the UK Renal Registry. Recently, similar data have become available for patients with chronic kidney disease. Data collected from a large population-based registry in Alberta, Canada and stratified for different levels of estimated GFR (eGFR) have shown that the reduction in life expectancy with kidney failure is not a uremic event associated with starting dialysis but a continuous process that is evident from an eGFR of ≤60 ml/min. Nevertheless, despite the poor prognosis of the last stages of renal failure, progress in the treatment and management of these patients and, in particular, of their cardiovascular risk factors continues to improve long-term outcome.
Databáze: OpenAIRE
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