Comparative toxicity of two glyphosate-based formulations to Eisenia andrei under laboratory conditions
| Autor: | E. M. Kesten, María Luisa Oneto, Lucas Piola, Silvana Basack, Julio Fuchs, Norma Casabé |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Environmental Engineering
Health Toxicology and Mutagenesis Eisenia andrei Glycine Median lethal dose Risk Assessment Lethal Dose 50 chemistry.chemical_compound Environmental Chemistry Animals Soil Pollutants Oligochaeta Active ingredient biology Herbicides Public Health Environmental and Occupational Health General Medicine General Chemistry biology.organism_classification Pollution Bioavailability Comet assay chemistry Glyphosate Environmental chemistry Bioaccumulation Toxicity Laboratories |
| Zdroj: | Chemosphere. 91(4) |
| ISSN: | 1879-1298 |
| Popis: | Glyphosate-based products are the leading post-emergent agricultural herbicides in the world, particularly in association with glyphosate tolerant crops. However, studies on the effects of glyphosate-based formulations on terrestrial receptors are scarce. This study was conducted to evaluate the comparative toxicity of two glyphosate-based products: Roundup FG (monoammonium salt, 72% acid equivalent, glyphosate-A) and Mon 8750 (monoammonium salt, 85.4% acid equivalent, glyphosate-B), towards the earthworm Eisenia andrei. Median lethal concentration (LC50) showed that glyphosate-A was 4.5-fold more toxic than glyphosate-B. Sublethal concentrations caused a concentration-dependent weight loss, consistent with the reported effect of glyphosate as uncoupler of oxidative phosphorylation. Glyphosate-A showed deleterious effects on DNA and lysosomal damage at concentrations close to the applied environmental concentrations (14.4 μg ae cm(-2)). With glyphosate-B toxic effects were observed at higher doses, close to its LC50, suggesting that the higher toxicity of formulate A could be attributed to the effects of some of the so-called "inert ingredients", either due to a direct intrinsic toxicity, or to an enhancement in the bioavailability and/or bioaccumulation of the active ingredient. Our results highlight the importance of ecotoxicological assessment not only of the active ingredients, but also of the different formulations usually employed in agricultural practices. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect